Transcription factor

B7Z6M2

Zinc finger protein 227

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 720 aa

96 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)92

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	68.2% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	67.0% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	67.0% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	67.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	65.8% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	65.4% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	64.7% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	64.7% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	64.7% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	62.3% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	61.1% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.0% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	60.6% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	59.8% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	59.4% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.4% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	59.0% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	58.6% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	58.2% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	57.9% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	57.8% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	57.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	57.8% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	57.7% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	57.4% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	57.2% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	56.7% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	56.5% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	56.5% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	56.3% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	56.2% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	56.2% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	56.0% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	56.0% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	55.9% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	55.8% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.7% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	55.7% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	55.5% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.4% identity		Open · Scan
M08935_2.00	NN 70-40%	CisBP	CCTCCTCCCTCAGACC	55.3% identity		Open · Scan
M00645_2.00	NN 70-40%	CisBP	CGCCCACGCA	54.8% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	54.8% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	54.8% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	54.7% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	54.4% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	54.4% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	54.4% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	54.2% identity		Open · Scan
M07666_2.00	NN 70-40%	CisBP	ATCTAGCCCCTGCCTACC	53.9% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	53.4% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	53.3% identity		Open · Scan
M02896_2.00	NN 70-40%	CisBP	TGCTTTCTAGGAATTCA	52.9% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	52.9% identity		Open · Scan
MA0731.1	NN 70-40%	JASPAR	TGCTTTCTAGGAATTCA	52.9% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	52.8% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	52.8% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	52.7% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	52.6% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	52.6% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	52.3% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	52.3% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	52.3% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	52.0% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	52.0% identity		Open · Scan
M02731_2.00	NN 70-40%	CisBP	CACTTTCACTTT	51.9% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	51.9% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	51.9% identity		Open · Scan
MA0508.1	NN 70-40%	JASPAR	AGAAAGTGAAAGTGA	51.9% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	51.6% identity		Open · Scan
M07733_2.00	NN 70-40%	CisBP	TCTTTCTCTCTCTCC	51.6% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	51.6% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	51.5% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	51.5% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	51.4% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	51.3% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	51.3% identity		Open · Scan
M07699_2.00	NN 70-40%	CisBP	GGTTTAT	51.1% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	51.0% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	51.0% identity		Open · Scan
M00134_2.00	NN 70-40%	CisBP	GCCACGCCCA	50.8% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	50.7% identity		Open · Scan
M08357_2.00	NN 70-40%	CisBP	GAGCCTGCTACTGAGCCTGGG	50.7% identity		Open · Scan
M08390_2.00	NN 70-40%	CisBP	GCTTTGTTGACTCAC	50.7% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	50.7% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	50.5% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	50.5% identity		Open · Scan
M07679_2.00	NN 70-40%	CisBP	TGCGATCTC	50.5% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	50.3% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	50.3% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	50.2% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	50.0% identity		Open · Scan

ModCRE4

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_tr_B7Z6M2_B7Z6M2_HUMAN:254:407_2i13_A_1	ModCRE	Homology model	GTGAAGTTGAAGGCTTTTGAT	Region 254-407 · 1 3D model		Open · Scan
TFS_tr_B7Z6M2_B7Z6M2_HUMAN:298:576_5wjq_D_1	ModCRE	Homology model	TGGATACCCCCCCACCCTCGCCCCCCAA	Region 298-576 · 1 3D model		Open · Scan
TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3j_E_1	ModCRE	Homology model	CTCCAGGGTTTTGCCCCACCCGGGAA	Region 356-632 · 1 3D model		Open · Scan
TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3m_C_1	ModCRE	Homology model	CGGACCCGTCTTCCCCCCCCCCCCGA	Region 356-632 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 720 aa

254-655

Region 254-655 4 PWM

Residues

402 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

6 active PDB models 6 summary rows

Region 254-6556 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_B7Z6M2_B7Z6M2_HUMAN:439:490_1llm_D_1	1llm	439-490	View model · PDB
Predicted = Low	TFS_tr_B7Z6M2_B7Z6M2_HUMAN:254:407_2i13_A_1	2i13	254-407	View model · PDB
Predicted = Low	TFS_tr_B7Z6M2_B7Z6M2_HUMAN:298:576_5wjq_D_1	5wjq	298-576	View model · PDB
Predicted = Low	TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3j_E_1	5v3j	356-632	View model · PDB
Predicted = Low	TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3m_C_1	5v3m	356-632	View model · PDB
Predicted = Low	TFS_tr_B7Z6M2_B7Z6M2_HUMAN:357:655_7w1m_H_1	7w1m	357-655	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	242:655	254	407	P:A · DNA:C,D	61.0% / 64.9%	100	View · PDB TFS_tr_B7Z6M2_B7Z6M2_HUMAN:254:407_2i13_A_1
1	5wjq	242:655	298	576	P:D · DNA:A,B	52.3% / 70.3%	99	View · PDB TFS_tr_B7Z6M2_B7Z6M2_HUMAN:298:576_5wjq_D_1
2	5v3m	242:655	356	632	P:C · DNA:A,B	52.3% / 68.2%	100	View · PDB TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3m_C_1
3	5v3j	242:655	356	632	P:E · DNA:A,B	52.3% / 68.2%	100	View · PDB TFS_tr_B7Z6M2_B7Z6M2_HUMAN:356:632_5v3j_E_1
1	1llm	242:655	439,439	490,490	P:C,D · DNA:A,B	50.0% / 65.4%	59,61	View · PDB DIMER_tr_B7Z6M2_B7Z6M2_HUMAN:439:490_1llm_D_1
5	7w1m	242:655	357	655	P:H · DNA:F,G	35.1% / 48.1%	92	View · PDB TFS_tr_B7Z6M2_B7Z6M2_HUMAN:357:655_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
245-267	PF00096	Zinc finger, C2H2 type	overlaps 254-655
273-295	PF00096	Zinc finger, C2H2 type	overlaps 254-655
301-323	PF00096	Zinc finger, C2H2 type	overlaps 254-655
329-351	PF00096	Zinc finger, C2H2 type	overlaps 254-655
357-379	PF00096	Zinc finger, C2H2 type	overlaps 254-655
385-407	PF00096	Zinc finger, C2H2 type	overlaps 254-655
413-435	PF00096	Zinc finger, C2H2 type	overlaps 254-655
441-463	PF00096	Zinc finger, C2H2 type	overlaps 254-655
469-491	PF00096	Zinc finger, C2H2 type	overlaps 254-655
497-519	PF00096	Zinc finger, C2H2 type	overlaps 254-655
525-547	PF00096	Zinc finger, C2H2 type	overlaps 254-655
553-575	PF00096	Zinc finger, C2H2 type	overlaps 254-655
581-603	PF00096	Zinc finger, C2H2 type	overlaps 254-655
609-631	PF00096	Zinc finger, C2H2 type	overlaps 254-655
637-659	PF00096	Zinc finger, C2H2 type	overlaps 254-655
665-687	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
693-715	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions