ModCRE DB

Transcription factor

C6ZRK5 - TCF7L2

TCF7L2 isoform pFC8A_TCF7L2_ex1-11-13-14 (Transcription factor 7-like 2 (T-cell specific, HMG-box), isoform CRA_i)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 579 aa

7 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M00198_2.00 NN 70+% CisBP AGATCAAAGG 99.0% identity Open · Scan
M08167_2.00 NN 70+% CisBP AAAGATCAAAGGAA 96.2% identity Open · Scan
MA0523.1 NN 70+% JASPAR AAAGATCAAAGGAA 93.5% identity Open · Scan
Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
MA1421.1 NN 70-40% JASPAR AAAGATCAAAGG 62.1% identity Open · Scan
MA0522.1 NN 70-40% JASPAR CACAGCTGCAG 59.3% identity Open · Scan
MA0768.1 NN 70-40% JASPAR AAAGATCAAAGGGTT 58.7% identity Open · Scan
M09392_2.00 NN 70-40% CisBP TCCTTTGATTTGCT 53.7% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 579 aa
326-397

Region 326-397 0 PWM

Residues
72 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
3U2B
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 326-3971 model
Actions
Predicted = Low TFS_C6ZRK5:326:397_3u2b_C_1 3u2b 326-397 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
5-236PF08347N-terminal CTNNB1 bindingNo overlap with loaded model regions
327-395PF00505HMG (high mobility group) boxoverlaps 326-397
422-449PF27556Zinc finger protein 704 C-terminal domainNo overlap with loaded model regions