ModCRE DB

Transcription factor

D2CFI5

CRX like homeobox 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 508 aa

22 Generated PWM 15 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M03250_2.00 NN 70-40% CisBP TTAATCCG 53.4% identity Open · Scan
MA0711.1 NN 70-40% JASPAR TTAATCCG 53.4% identity Open · Scan
M03076_2.00 NN 70-40% CisBP TTAATTAAATTAA 50.8% identity Open · Scan
MA0874.1 NN 70-40% JASPAR GTCCATTAATTAATGGA 50.8% identity Open · Scan
M06291_2.00 NN 70-40% CisBP TTAATTA 50.0% identity Open · Scan
M09208_2.00 NN 70-40% CisBP CCTAATCCTCTTA 50.0% identity Open · Scan
M09569_2.00 NN 70-40% CisBP GTTAATCCCT 50.0% identity Open · Scan
MA0467.1 NN 70-40% JASPAR AAGAGGATTAG 50.0% identity Open · Scan
ModCRE14
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_D2CFI5_D2CFI5_HUMAN:60:119_1puf_A_1 ModCRE Homology model TTTTTAATTAATTATATGG Region 60-119 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:61:120_1fjl_A_1 ModCRE Homology model TTAATTAAATTAG Region 61-120 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:64:122_2r5z_A_1 ModCRE Homology model CCGGATAATTAATTACTCA Region 64-122 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:65:122_2r5y_A_1 ModCRE Homology model CAAGGTAATAAATTAATCA Region 65-122 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:119_4qtr_A_1 ModCRE Homology model GCAAATTTATTGC Region 66-119 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_1b8i_A_1 ModCRE Homology model GGTAATTAATCAC Region 66-120 · 1 3D model Open · Scan
DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_4uus_A_1 ModCRE Homology model GGTAATTTATTTG Region 66-120 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:62:116_2lkx_A_1 ModCRE Homology model TCATTTATTCCCC Region 62-116 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:62:117_1fjl_B_1 ModCRE Homology model CGGCCCTAATTAA Region 62-117 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:62:120_3cmy_A_1 ModCRE Homology model TATAATA Region 62-120 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:62:127_1ahd_P_1 ModCRE Homology model ATTAAATGGTTTTT Region 62-127 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:63:119_1ig7_A_1 ModCRE Homology model TATTAATTAAATT Region 63-119 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:66:119_4qtr_A_1 ModCRE Homology model GCAAATTAATTGC Region 66-119 · 1 3D model Open · Scan
TFS_tr_D2CFI5_D2CFI5_HUMAN:66:120_1b8i_A_1 ModCRE Homology model ACCAATTTTTTTT Region 66-120 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 508 aa
60-127

Region 60-127 14 PWM

Residues
68 aa
Domains
PF00046 · Homeodomain
3D models
15 active PDBs · 10 summary rows
Templates
1AHD, 1B8I, 1FJL, 1IG7, 1PUF, 2LKX, 2R5Y, 2R5Z, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
15 active PDB models 10 summary rows
Region 60-12715 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:60:119_1puf_A_1 1puf 60-119 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:61:120_1fjl_A_1 1fjl 61-120 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:64:122_2r5z_A_1 2r5z 64-122 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:65:122_2r5y_A_1 2r5y 65-122 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:119_4qtr_A_1 4qtr 66-119 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_1b8i_A_1 1b8i 66-120 View model · PDB
Predicted = Low DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_4uus_A_1 4uus 66-120 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:61:120_1fjl_A_1 1fjl 61-120 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:62:116_2lkx_A_1 2lkx 62-116 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:62:117_1fjl_B_1 1fjl 62-117 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:62:120_3cmy_A_1 3cmy 62-120 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:62:127_1ahd_P_1 1ahd 62-127 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:63:119_1ig7_A_1 1ig7 63-119 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:66:119_4qtr_A_1 4qtr 66-119 View model · PDB
Predicted = Low TFS_tr_D2CFI5_D2CFI5_HUMAN:66:120_1b8i_A_1 1b8i 66-120 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 2lkx 58:135 62 116 P:A · DNA:B,C 45.5% / 69.1% 80 View · PDB TFS_tr_D2CFI5_D2CFI5_HUMAN:62:116_2lkx_A_1
1 1fjl 58:135 61,62 120,117 P:A,B · DNA:D,E 43.3% / 68.3% 92,98 View · PDB TFS_tr_D2CFI5_D2CFI5_HUMAN:61:120_1fjl_A_1
1 1fjl 58:135 61,62 120,117 P:A,B · DNA:D,E 43.3% / 68.3% 92,98 View · PDB DIMER_tr_D2CFI5_D2CFI5_HUMAN:61:120_1fjl_A_1
4 1ig7 58:135 63 119 P:A · DNA:B,C 42.1% / 63.2% 98 View · PDB TFS_tr_D2CFI5_D2CFI5_HUMAN:63:119_1ig7_A_1
3 4uus 58:135 66,86 120,116 P:A,B · DNA:C,D 41.8% / 60.0% 82,44 View · PDB DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_4uus_A_1
4 1b8i 58:135 66,86 120,116 P:A,B · DNA:C,D 41.8% / 60.0% 88,53 View · PDB DIMER_tr_D2CFI5_D2CFI5_HUMAN:66:120_1b8i_A_1
3 3cmy 58:135 62 120 P:A · DNA:B,C 40.7% / 61.0% 98 View · PDB TFS_tr_D2CFI5_D2CFI5_HUMAN:62:120_3cmy_A_1
5 2r5z 58:135 64,86 122,116 P:A,B · DNA:C,D 39.0% / 62.7% 78,52 View · PDB DIMER_tr_D2CFI5_D2CFI5_HUMAN:64:122_2r5z_A_1
2 1puf 58:135 60,63 119,116 P:A,B · DNA:D,E 38.3% / 63.3% 77,73 View · PDB DIMER_tr_D2CFI5_D2CFI5_HUMAN:60:119_1puf_A_1
5 1ahd 58:135 62 127 P:P · DNA:A,B 34.8% / 60.6% 97 View · PDB TFS_tr_D2CFI5_D2CFI5_HUMAN:62:127_1ahd_P_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
63-116PF00046Homeodomainoverlaps 60-127