ModCRE DB

Transcription factor

E2GH23 - TCF7L2

T-cell factor-4 variant E

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 596 aa

7 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M08167_2.00 NN 70+% CisBP AAAGATCAAAGGAA 99.7% identity Open · Scan
M00198_2.00 NN 70+% CisBP AGATCAAAGG 99.3% identity Open · Scan
MA0523.1 NN 70+% JASPAR AAAGATCAAAGGAA 96.1% identity Open · Scan
Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
MA1421.1 NN 70-40% JASPAR AAAGATCAAAGG 60.0% identity Open · Scan
MA0768.1 NN 70-40% JASPAR AAAGATCAAAGGGTT 59.0% identity Open · Scan
MA0522.1 NN 70-40% JASPAR CACAGCTGCAG 57.6% identity Open · Scan
M09392_2.00 NN 70-40% CisBP TCCTTTGATTTGCT 54.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 596 aa
326-397

Region 326-397 0 PWM

Residues
72 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
3U2B
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 326-3971 model
Actions
Predicted = Low TFS_E2GH23:326:397_3u2b_C_1 3u2b 326-397 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
5-236PF08347N-terminal CTNNB1 bindingNo overlap with loaded model regions
327-395PF00505HMG (high mobility group) boxoverlaps 326-397
439-466PF27556Zinc finger protein 704 C-terminal domainNo overlap with loaded model regions