ModCRE DB

Transcription factor

E7ESP8 - ZEB2

Zinc finger E-box binding homeobox 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 467 aa

28 Generated PWM 10 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)18
MotifPredictionSourceDNA bindingSupportLogoActions
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 61.5% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 61.5% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 61.5% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 61.5% identity Open · Scan
M07842_2.00 NN 70-40% CisBP CTCACCTG 60.6% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 57.5% identity Open · Scan
M04651_2.00 NN 70-40% CisBP TTCACTATTATAGTGAA 57.5% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 57.3% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 56.8% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 56.2% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 55.1% identity Open · Scan
M00019_2.00 NN 70-40% CisBP ACCCCTAATT 54.0% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 53.6% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 53.3% identity Open · Scan
M01468_2.00 NN 70-40% CisBP TTACCCCTGA 50.0% identity Open · Scan
M01531_2.00 NN 70-40% CisBP CCCCCCCTAAAT 50.0% identity Open · Scan
M07625_2.00 NN 70-40% CisBP TCTCTCTCTCTCTCTCTCTCTCTCTCTCTC 50.0% identity Open · Scan
M08295_2.00 NN 70-40% CisBP CTGCTGGAATCTCCA 50.0% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_E7ESP8_E7ESP8_HUMAN:308:356_1llm_C_1 ModCRE Homology model TAGGCGCGCGGA Region 308-356 · 1 3D model Open · Scan
DIMER_tr_E7ESP8_E7ESP8_HUMAN:372:402_3coq_B_1 ModCRE Homology model AATAACTGTTAA Region 372-402 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:292_5k5l_F_1 ModCRE Homology model GTAACACACGGGTA Region 241-292 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5kkq_A_1 ModCRE Homology model TTCCACTAACTAGCCGG Region 241-360 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t00_A_1 ModCRE Homology model TCTCCACGCGCTGCCGG Region 241-360 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t0u_A_1 ModCRE Homology model TTCCCCTAGCGCTGCGCGATCC Region 241-360 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5yef_A_1 ModCRE Homology model ACAAACCGGGGGCCCGGGAAATT Region 241-360 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_8sss_A_1 ModCRE Homology model TTTCGCAGGGCGCGCCAGGTTC Region 241-360 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:308:357_4gzn_C_1 ModCRE Homology model GGGCCCCCCC Region 308-357 · 1 3D model Open · Scan
TFS_tr_E7ESP8_E7ESP8_HUMAN:308:357_4m9v_C_1 ModCRE Homology model GCCCCCCCCC Region 308-357 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 467 aa
241-360
372-402

Region 241-360 9 PWM

Residues
120 aa
Domains
PF05605 · Drought induced 19 protein (Di19), zinc-binding PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
9 active PDBs · 6 summary rows
Templates
1LLM, 4GZN, 4M9V, 5K5L, 5KKQ, 5T00, 5T0U, 5YEF, ...
Sources
Predicted = Low
Scan this region Show models

Region 372-402 1 PWM

Residues
31 aa
Domains
No overlapping PFAM annotation recorded
3D models
1 active PDB
Templates
3COQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
10 active PDB models 6 summary rows
Region 241-3609 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_E7ESP8_E7ESP8_HUMAN:308:356_1llm_C_1 1llm 308-356 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:292_5k5l_F_1 5k5l 241-292 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5kkq_A_1 5kkq 241-360 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t00_A_1 5t00 241-360 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t0u_A_1 5t0u 241-360 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5yef_A_1 5yef 241-360 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_8sss_A_1 8sss 241-360 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:308:357_4gzn_C_1 4gzn 308-357 View model · PDB
Predicted = Low TFS_tr_E7ESP8_E7ESP8_HUMAN:308:357_4m9v_C_1 4m9v 308-357 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1llm 241:364 308,308 356,356 P:C,D · DNA:A,B 36.7% / 55.1% 56,57 View · PDB DIMER_tr_E7ESP8_E7ESP8_HUMAN:308:356_1llm_C_1
1 5kkq 241:364 241 360 P:A · DNA:B,C 36.7% / 51.7% 72 View · PDB TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5kkq_A_1
2 5t00 241:364 241 360 P:A · DNA:B,C 36.7% / 51.7% 74 View · PDB TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t00_A_1
3 5t0u 241:364 241 360 P:A · DNA:B,C 36.7% / 51.7% 62 View · PDB TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5t0u_A_1
4 5yef 241:364 241 360 P:A · DNA:C,D 36.7% / 51.7% 62 View · PDB TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_5yef_A_1
5 8sss 241:364 241 360 P:A · DNA:B,C 36.7% / 51.7% 53 View · PDB TFS_tr_E7ESP8_E7ESP8_HUMAN:241:360_8sss_A_1
Region 372-4021 model
Actions
Predicted = Low DIMER_tr_E7ESP8_E7ESP8_HUMAN:372:402_3coq_B_1 3coq 372-402 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
239-290PF05605Drought induced 19 protein (Di19), zinc-bindingoverlaps 241-360
310-332PF00096Zinc finger, C2H2 typeoverlaps 241-360
338-358PF00096Zinc finger, C2H2 typeoverlaps 241-360