ModCRE DB

Transcription factor

E7EVZ1 - ZFHX4

Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 3590 aa

23 Generated PWM 20 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M02108_2.00 NN 70-40% CisBP CCTAATTAG 56.4% identity Open · Scan
M06304_2.00 NN 70-40% CisBP TTAATTA 56.1% identity Open · Scan
M02182_2.00 NN 70-40% CisBP TTAATTAGC 52.6% identity Open · Scan
M01849_2.00 NN 70-40% CisBP ACTAATTAG 52.4% identity Open · Scan
M05065_2.00 NN 70-40% CisBP TTAACGAG 50.8% identity Open · Scan
M09137_2.00 NN 70-40% CisBP ATTAATTAATTTT 50.8% identity Open · Scan
MA0135.1 NN 70-40% JASPAR AAATTAATTAATC 50.8% identity Open · Scan
MA0704.1 NN 70-40% JASPAR TTAATTAA 50.8% identity Open · Scan
ModCRE15
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2104:2153_2hdd_B_1 ModCRE Homology model CGCCCATAATTAACCCA Region 2104-2153 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2104:2160_5hod_A_1 ModCRE Homology model TTAATTTTTGGTGATCTA Region 2104-2160 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2200:2253_3d1n_L_1 ModCRE Homology model TAGTTTAATTAATA Region 2200-2253 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2200:2259_1fjl_A_1 ModCRE Homology model CTGATGCCATCCG Region 2200-2259 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2204:2258_1hdd_D_1 ModCRE Homology model CCCCATTAATTATTAAA Region 2204-2258 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2204:2258_3hdd_A_1 ModCRE Homology model CCCCCTTAATTGGGCAA Region 2204-2258 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2552:2636_3l1p_B_1 ModCRE Homology model CTAAAAAAAATTTTTTTTAAGG Region 2552-2636 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2580:2636_5hod_A_1 ModCRE Homology model TCAATTAATGGTCATGAG Region 2580-2636 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2904:2960_3a01_B_1 ModCRE Homology model CCCCTAATTAATTAAAA Region 2904-2960 · 1 3D model Open · Scan
DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2905:2960_3hdd_B_1 ModCRE Homology model GGGCCTTAATTGGCCAA Region 2905-2960 · 1 3D model Open · Scan
TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5t0u_A_1 ModCRE Homology model GGGCCTTTGACGCGAGC Region 1513-1586 · 1 3D model Open · Scan
TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5und_A_1 ModCRE Homology model CAACCAAAGTAATA Region 1513-1586 · 1 3D model Open · Scan
TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5yeh_A_1 ModCRE Homology model TACCCCTATTGAAG Region 1513-1586 · 1 3D model Open · Scan
TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1521:1587_2kmk_A_1 ModCRE Homology model GGGAATTGAAATCCAA Region 1521-1587 · 1 3D model Open · Scan
TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1560:1588_6ki6_A_1 ModCRE Homology model ATACTCGGAAA Region 1560-1588 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 3590 aa
1513-1588
2104-2160
2192-2960

Region 1513-1588 5 PWM

Residues
76 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
5 active PDBs
Templates
2KMK, 5T0U, 5UND, 5YEH, 6KI6
Sources
Predicted = Low
Scan this region Show models

Region 2104-2160 2 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
2 active PDBs
Templates
2HDD, 5HOD
Sources
Predicted = Low
Scan this region Show models

Region 2192-2960 8 PWM

Residues
769 aa
Domains
PF00046 · Homeodomain PF00046 · Homeodomain PF00046 · Homeodomain
3D models
13 active PDBs · 10 summary rows
Templates
1FJL, 1HDD, 2LKX, 3A01, 3D1N, 3HDD, 3L1P, 3LNQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
20 active PDB models 10 summary rows
Region 1513-15885 models
Actions
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5t0u_A_1 5t0u 1513-1586 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5und_A_1 5und 1513-1586 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1513:1586_5yeh_A_1 5yeh 1513-1586 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1521:1587_2kmk_A_1 2kmk 1521-1587 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:1560:1588_6ki6_A_1 6ki6 1560-1588 View model · PDB
Region 2104-21602 models
Actions
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2104:2153_2hdd_B_1 2hdd 2104-2153 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2104:2160_5hod_A_1 5hod 2104-2160 View model · PDB
Region 2192-296013 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2200:2253_3d1n_L_1 3d1n 2200-2253 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2200:2259_1fjl_A_1 1fjl 2200-2259 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2204:2258_1hdd_D_1 1hdd 2204-2258 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2204:2258_3hdd_A_1 3hdd 2204-2258 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2552:2636_3l1p_B_1 3l1p 2552-2636 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2580:2636_5hod_A_1 5hod 2580-2636 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2904:2960_3a01_B_1 3a01 2904-2960 View model · PDB
Predicted = Low DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2905:2960_3hdd_B_1 3hdd 2905-2960 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2199:2260_2lkx_A_1 2lkx 2199-2260 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2552:2636_3l1p_B_1 3l1p 2552-2636 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2580:2636_5hod_A_1 5hod 2580-2636 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2904:2960_3a01_B_1 3a01 2904-2960 View model · PDB
Predicted = Low TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2905:2960_3lnq_A_1 3lnq 2905-2960 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5hod 2552:2640 2580,2581 2636,2636 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PDB DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2580:2636_5hod_A_1
1 5hod 2552:2640 2580,2581 2636,2636 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PDB TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2580:2636_5hod_A_1
5 3hdd 2552:2640 2907,2905 2960,2960 P:A,B · DNA:C,D 42.9% / 62.5% 98,100 View · PDB DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2905:2960_3hdd_B_1
3 3lnq 2552:2640 2905 2960 P:A · DNA:B,C 42.9% / 60.7% 96 View · PDB TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2905:2960_3lnq_A_1
2 3a01 2552:2640 2192,2904 2257,2960 P:A,B · DNA:C,D 42.1% / 61.4% 84,100 View · PDB DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2904:2960_3a01_B_1
2 3a01 2552:2640 2192,2904 2257,2960 P:A,B · DNA:C,D 42.1% / 61.4% 84,100 View · PDB TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2904:2960_3a01_B_1
4 2lkx 2552:2640 2199 2260 P:A · DNA:B,C 40.3% / 53.2% 91 View · PDB TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2199:2260_2lkx_A_1
4 3d1n 2552:2640 2200,2200 2253,2253 P:K,L · DNA:C,D 38.9% / 51.9% 36,37 View · PDB DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2200:2253_3d1n_L_1
3 3l1p 2552:2640 2552,2552 2636,2636 P:A,B · DNA:M,N 32.9% / 51.8% 55,55 View · PDB DIMER_tr_E7EVZ1_E7EVZ1_HUMAN:2552:2636_3l1p_B_1
5 3l1p 2552:2640 2552,2552 2636,2636 P:A,B · DNA:M,N 32.9% / 51.8% 55,55 View · PDB TFS_tr_E7EVZ1_E7EVZ1_HUMAN:2552:2636_3l1p_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
699-723PF12874Zinc-finger of C2H2 typeNo overlap with loaded model regions
973-997PF24056Zinc finger homeobox protein 3-like, C2H2 type zinc-fingerNo overlap with loaded model regions
1567-1591PF00096Zinc finger, C2H2 typeoverlaps 1513-1588
2104-2160PF00046Homeodomainoverlaps 2104-2160
2201-2257PF00046Homeodomainoverlaps 2192-2960
2580-2636PF00046Homeodomainoverlaps 2192-2960
2904-2960PF00046Homeodomainoverlaps 2192-2960