ModCRE DB

Transcription factor

E7EW59 - SALL2

Sal-like protein 2 (Zinc finger protein Spalt-2)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 906 aa

34 Generated PWM 14 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)21
MotifPredictionSourceDNA bindingSupportLogoActions
M08979_2.00 NN 70-40% CisBP CCCACCCTCC 68.4% identity Open · Scan
M00641_2.00 NN 70-40% CisBP ATTGACCACT 60.0% identity Open · Scan
M03702_2.00 NN 70-40% CisBP GACCCCCCACGACGC 56.6% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 54.7% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 54.7% identity Open · Scan
M01022_2.00 NN 70-40% CisBP GGACCACCCAC 53.8% identity Open · Scan
M01024_2.00 NN 70-40% CisBP GGACCACCCA 53.8% identity Open · Scan
MA0734.1 NN 70-40% JASPAR GCGACCACACTG 53.8% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 52.8% identity Open · Scan
M00954_2.00 NN 70-40% CisBP CTACCCTA 52.5% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 51.2% identity Open · Scan
M00608_2.00 NN 70-40% CisBP CCTGTTG 51.0% identity Open · Scan
M03691_2.00 NN 70-40% CisBP ATGCAACAGGTGG 50.9% identity Open · Scan
M06087_2.00 NN 70-40% CisBP ACCACCTGTTGCA 50.9% identity Open · Scan
M10203_2.00 NN 70-40% CisBP CCCCAAACCACCCC 50.8% identity Open · Scan
MA0073.1 NN 70-40% JASPAR CCCCAAACCACCCCCCCCCA 50.8% identity Open · Scan
M00765_2.00 NN 70-40% CisBP CCCGCCCCC 50.0% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 50.0% identity Open · Scan
M05859_2.00 NN 70-40% CisBP GGCCACGCCCACT 50.0% identity Open · Scan
MA0685.1 NN 70-40% JASPAR TAAGCCACGCCCCCTTT 50.0% identity Open · Scan
MA0744.1 NN 70-40% JASPAR ATGCAACAGGTGG 50.0% identity Open · Scan
ModCRE13
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8a4i_I_1 ModCRE Homology model AGGTCGGGGCG Region 235-286 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8cuc_F_1 ModCRE Homology model GGGGGGGGAGTT Region 235-286 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:237:286_3uk3_C_1 ModCRE Homology model GATGGGAATGT Region 237-286 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:237:286_4is1_C_1 ModCRE Homology model AACCTGAATGT Region 237-286 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:237:288_4is1_D_1 ModCRE Homology model TGTGTCCACC Region 237-288 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:237:293_8e3e_A_1 ModCRE Homology model GGACGGGCACCTTAA Region 237-293 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:493:544_5yj3_C_1 ModCRE Homology model TGTGG Region 493-544 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e93_A_1 ModCRE Homology model GCCGGCGGCGAGGATG Region 493-578 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e94_A_1 ModCRE Homology model GCCCGCGGCCGGGGTA Region 493-578 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:495:544_3uk3_C_1 ModCRE Homology model TCATCATGTGA Region 495-544 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:495:544_3uk3_D_1 ModCRE Homology model TGCATCCGGC Region 495-544 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:495:544_4is1_C_1 ModCRE Homology model ACATGATTTCT Region 495-544 · 1 3D model Open · Scan
TFS_tr_E7EW59_E7EW59_HUMAN:495:544_4is1_D_1 ModCRE Homology model AGCAATCACC Region 495-544 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 906 aa
235-293
493-578

Region 235-293 6 PWM

Residues
59 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 4 summary rows
Templates
1LLM, 3UK3, 4IS1, 8A4I, 8CUC, 8E3E
Sources
Predicted = Low
Scan this region Show models

Region 493-578 7 PWM

Residues
86 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 2 summary rows
Templates
3UK3, 4IS1, 5YJ3, 6E93, 6E94
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
14 active PDB models 6 summary rows
Region 235-2937 models · 4 summary rows
Actions
Predicted = Low DIMER_tr_E7EW59_E7EW59_HUMAN:237:282_1llm_D_1 1llm 237-282 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8a4i_I_1 8a4i 235-286 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8cuc_F_1 8cuc 235-286 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:237:286_3uk3_C_1 3uk3 237-286 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:237:286_4is1_C_1 4is1 237-286 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:237:288_4is1_D_1 4is1 237-288 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:237:293_8e3e_A_1 8e3e 237-293 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 8cuc 233:305 235 286 P:F · DNA:A,B 61.5% / 75.0% 96 View · PDB TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8cuc_F_1
2 8a4i 233:305 235 286 P:I · DNA:A,B 61.5% / 75.0% 96 View · PDB TFS_tr_E7EW59_E7EW59_HUMAN:235:286_8a4i_I_1
5 8e3e 233:305 237 293 P:A · DNA:X,Y 45.6% / 63.2% 51 View · PDB TFS_tr_E7EW59_E7EW59_HUMAN:237:293_8e3e_A_1
1 1llm 233:305 237,237 282,282 P:C,D · DNA:A,B 39.1% / 58.7% 52,54 View · PDB DIMER_tr_E7EW59_E7EW59_HUMAN:237:282_1llm_D_1
Region 493-5787 models · 2 summary rows
Actions
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:493:544_5yj3_C_1 5yj3 493-544 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e93_A_1 6e93 493-578 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e94_A_1 6e94 493-578 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:495:544_3uk3_C_1 3uk3 495-544 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:495:544_3uk3_D_1 3uk3 495-544 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:495:544_4is1_C_1 4is1 495-544 View model · PDB
Predicted = Low TFS_tr_E7EW59_E7EW59_HUMAN:495:544_4is1_D_1 4is1 495-544 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
3 6e93 233:305 493 578 P:A · DNA:C,D 38.4% / 52.3% 73 View · PDB TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e93_A_1
4 6e94 233:305 493 578 P:A · DNA:C,D 38.4% / 52.3% 73 View · PDB TFS_tr_E7EW59_E7EW59_HUMAN:493:578_6e94_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
264-286PF00096Zinc finger, C2H2 typeoverlaps 235-293
522-544PF00096Zinc finger, C2H2 typeoverlaps 493-578
555-576PF00096Zinc finger, C2H2 typeoverlaps 493-578
776-799PF13912C2H2-type zinc fingerNo overlap with loaded model regions