Transcription factor

E9PMU6 - KRABD5

KRAB box domain containing 5

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 541 aa

96 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)86

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	68.7% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	68.2% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	68.2% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	67.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	65.8% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	65.8% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	65.8% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	65.8% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	65.8% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	65.4% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	64.7% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	63.5% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	63.5% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	60.5% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	60.2% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	60.1% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	58.7% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	58.4% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	58.2% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	57.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	57.5% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	57.5% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	57.5% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	57.1% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	57.1% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	56.8% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	56.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	56.5% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	56.2% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	56.2% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.6% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.6% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.6% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	55.4% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	55.4% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	55.1% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	54.5% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	54.5% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	54.4% identity		Open · Scan
M07656_2.00	NN 70-40%	CisBP	TGTCTAGTAAGTCTA	54.4% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	54.3% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	54.2% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	54.0% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	53.7% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	53.6% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	53.4% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	53.3% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	53.2% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	53.0% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	53.0% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	52.9% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	52.6% identity		Open · Scan
M01181_2.00	NN 70-40%	CisBP	GCGCATCCCC	52.5% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	52.5% identity		Open · Scan
M07628_2.00	NN 70-40%	CisBP	AGTGGTTCTGCTTCT	52.4% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	52.3% identity		Open · Scan
M08921_2.00	NN 70-40%	CisBP	CCTCATTCTTCTTGGACATG	52.3% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	52.2% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	52.1% identity		Open · Scan
M07633_2.00	NN 70-40%	CisBP	CTCTCGTTGTGCCTTTGCCAT	52.1% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	51.6% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	51.5% identity		Open · Scan
M07684_2.00	NN 70-40%	CisBP	CCTGTTCTTGACTTT	51.4% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	51.3% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	51.2% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	51.2% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	51.2% identity		Open · Scan
M07687_2.00	NN 70-40%	CisBP	ACAAATAAGGTTCTTGTGCCCCCTGCT	51.1% identity		Open · Scan
M08540_2.00	NN 70-40%	CisBP	CCCCT	51.1% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	51.0% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	50.9% identity		Open · Scan
M07717_2.00	NN 70-40%	CisBP	GGCTCCGCCCCC	50.9% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	50.8% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	50.8% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	50.8% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	50.7% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	50.3% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	50.2% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	50.2% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	50.1% identity		Open · Scan
M00779_2.00	NN 70-40%	CisBP	GCCACGCCCA	50.0% identity		Open · Scan
M03702_2.00	NN 70-40%	CisBP	GACCCCCCACGACGC	50.0% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	50.0% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	50.0% identity		Open · Scan
M08867_2.00	NN 70-40%	CisBP	CACCCCCTG	50.0% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	50.0% identity		Open · Scan

ModCRE10

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5v3j_E_1	ModCRE	Homology model	ATAATGGCTAACTTCTGTA	Region 134-228 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5v3m_C_1	ModCRE	Homology model	AACTCGCGCTTATGTGGT	Region 134-228 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5wjq_D_1	ModCRE	Homology model	ATTCTAGGCACGTGTTGGT	Region 134-228 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:140:228_5eh2_F_1	ModCRE	Homology model	CCGCGGCGGGGGGCCCCCC	Region 140-228 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:141:228_2i13_A_1	ModCRE	Homology model	AGTATTAACCTGCCGAAT	Region 141-228 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:231:341_5ei9_E_1	ModCRE	Homology model	GCCCCCGGGGGGGGGGCA	Region 231-341 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3j_E_1	ModCRE	Homology model	CCCCCCGGTGGCACCAAGGTGTGGAA	Region 233-509 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3m_C_1	ModCRE	Homology model	CCCGGGGGGGGGGGGCGGGGGGGGAG	Region 233-509 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:259:537_5wjq_D_1	ModCRE	Homology model	GGGCGGGGGGGGGGGGGGGGGGGGTCGC	Region 259-537 · 1 3D model		Open · Scan
TFS_tr_E9PMU6_E9PMU6_HUMAN:299:452_2i13_A_1	ModCRE	Homology model	CTTCAGCTTCTAGTCCTACAA	Region 299-452 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 541 aa

134-228

231-537

Region 134-228 5 PWM

Residues

95 aa

Domains

No overlapping PFAM annotation recorded

3D models

5 active PDBs

Templates

2I13, 5EH2, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

Region 231-537 5 PWM

Residues

307 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

7 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

12 active PDB models 6 summary rows

Region 134-2285 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5v3j_E_1	5v3j	134-228	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5v3m_C_1	5v3m	134-228	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:134:228_5wjq_D_1	5wjq	134-228	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:140:228_5eh2_F_1	5eh2	140-228	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:141:228_2i13_A_1	2i13	141-228	View model · PDB

Region 231-5377 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_E9PMU6_E9PMU6_HUMAN:483:535_1llm_C_1	1llm	483-535	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:231:341_5ei9_E_1	5ei9	231-341	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3j_E_1	5v3j	233-509	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3m_C_1	5v3m	233-509	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:234:532_7w1m_H_1	7w1m	234-532	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:259:537_5wjq_D_1	5wjq	259-537	View model · PDB
Predicted = Low	TFS_tr_E9PMU6_E9PMU6_HUMAN:299:452_2i13_A_1	2i13	299-452	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	228:537	299	452	P:A · DNA:C,D	59.7% / 68.8%	100	View · PDB TFS_tr_E9PMU6_E9PMU6_HUMAN:299:452_2i13_A_1
1	5wjq	228:537	259	537	P:D · DNA:A,B	56.6% / 72.4%	99	View · PDB TFS_tr_E9PMU6_E9PMU6_HUMAN:259:537_5wjq_D_1
2	5v3m	228:537	233	509	P:C · DNA:A,B	55.6% / 71.5%	100	View · PDB TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3m_C_1
3	5v3j	228:537	233	509	P:E · DNA:A,B	55.6% / 71.5%	100	View · PDB TFS_tr_E9PMU6_E9PMU6_HUMAN:233:509_5v3j_E_1
1	1llm	228:537	483,483	535,535	P:C,D · DNA:A,B	45.3% / 60.4%	60,62	View · PDB DIMER_tr_E9PMU6_E9PMU6_HUMAN:483:535_1llm_C_1
5	7w1m	228:537	234	532	P:H · DNA:F,G	33.8% / 49.4%	92	View · PDB TFS_tr_E9PMU6_E9PMU6_HUMAN:234:532_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
4-44	PF01352	KRAB box	No overlap with loaded model regions
234-256	PF00096	Zinc finger, C2H2 type	overlaps 231-537
262-284	PF00096	Zinc finger, C2H2 type	overlaps 231-537
290-312	PF00096	Zinc finger, C2H2 type	overlaps 231-537
318-340	PF00096	Zinc finger, C2H2 type	overlaps 231-537
346-368	PF00096	Zinc finger, C2H2 type	overlaps 231-537
374-396	PF00096	Zinc finger, C2H2 type	overlaps 231-537
402-424	PF00096	Zinc finger, C2H2 type	overlaps 231-537
430-452	PF00096	Zinc finger, C2H2 type	overlaps 231-537
458-480	PF00096	Zinc finger, C2H2 type	overlaps 231-537
486-508	PF00096	Zinc finger, C2H2 type	overlaps 231-537
514-536	PF00096	Zinc finger, C2H2 type	overlaps 231-537