ModCRE DB

Transcription factor

F8VS42 - NPAS3

Neuronal PAS domain-containing protein 3 (Basic-helix-loop-helix-PAS protein MOP6) (Member of PAS protein 6)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 935 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGC Region 160-416 · 1 3D model Open · Scan
DIMER_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1 ModCRE Homology model GCGTACACCGCGCCC Region 57-453 · 1 3D model Open · Scan
DIMER_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1 ModCRE Homology model GCGCGTACCGGCGGGGG Region 58-440 · 1 3D model Open · Scan
DIMER_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1 ModCRE Homology model CCGCACACGCGCCGGGGG Region 58-454 · 1 3D model Open · Scan
TFS_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGC Region 160-416 · 1 3D model Open · Scan
TFS_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1 ModCRE Homology model CCGTACACCGCGCCC Region 57-453 · 1 3D model Open · Scan
TFS_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1 ModCRE Homology model GCGCGTACCCGCGGGGG Region 58-440 · 1 3D model Open · Scan
TFS_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1 ModCRE Homology model GCGCACACGCGCCGGGGG Region 58-454 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 935 aa
57-454

Region 57-454 8 PWM

Residues
398 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 57-4548 models · 8 summary rows
Actions
Predicted = Low DIMER_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1 8osl 160-416 View model · PDB
Predicted = Low DIMER_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1 4zpk 57-453 View model · PDB
Predicted = Low DIMER_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1 4zpr 58-440 View model · PDB
Predicted = Low DIMER_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1 5sy7 58-454 View model · PDB
Predicted = Low TFS_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1 8osl 160-416 View model · PDB
Predicted = Low TFS_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1 4zpk 57-453 View model · PDB
Predicted = Low TFS_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1 4zpr 58-440 View model · PDB
Predicted = Low TFS_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1 5sy7 58-454 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 57:454 160,58 216,454 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB TFS_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1
1 5sy7 57:454 160,58 216,454 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB DIMER_tr_F8VS42_F8VS42_HUMAN:58:454_5sy7_B_1
3 4zpr 57:454 160,58 216,440 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB TFS_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1
3 4zpr 57:454 160,58 216,440 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB DIMER_tr_F8VS42_F8VS42_HUMAN:58:440_4zpr_B_1
2 4zpk 57:454 160,57 216,453 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB TFS_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1
2 4zpk 57:454 160,57 216,453 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB DIMER_tr_F8VS42_F8VS42_HUMAN:57:453_4zpk_B_1
4 8osl 57:454 160,59 416,107 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1
4 8osl 57:454 160,59 416,107 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_tr_F8VS42_F8VS42_HUMAN:160:416_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
57-117PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 57-454
158-218PF00989PAS foldoverlaps 57-454
349-436PF08447PAS foldoverlaps 57-454