ModCRE DB

Transcription factor

K7ER43 - ZNF426

Zinc finger protein 426

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 516 aa

41 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)31
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 63.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 63.0% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 63.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 62.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 62.3% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.3% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 61.1% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 60.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 59.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 59.0% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 57.2% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 57.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 57.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 56.9% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 56.8% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 53.6% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 53.2% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.8% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 52.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 52.2% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 51.5% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.4% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 51.4% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 51.2% identity Open · Scan
M07707_2.00 NN 70-40% CisBP TCCCGC 51.0% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.9% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 50.8% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 50.0% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_K7ER43_K7ER43_HUMAN:324:372_1llm_D_1 ModCRE Homology model TCGGCGCGCCGG Region 324-372 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5v3j_E_1 ModCRE Homology model CCGCGAGCTTTTCGGAA Region 102-230 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5v3m_C_1 ModCRE Homology model CCCCGGAGGTTTTTAGCTG Region 102-230 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5wjq_D_1 ModCRE Homology model CCCCCCCGGCTATGATCAC Region 102-230 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:110:208_5eh2_F_1 ModCRE Homology model GGGTGGTGGGTTAACCCAC Region 110-208 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:110:231_2i13_A_1 ModCRE Homology model AAATATAAAGTAACCCGCCCA Region 110-231 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:238:516_5wjq_D_1 ModCRE Homology model CCCTGGGGGGGGGGCGGGGGGAATCTCT Region 238-516 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3j_E_1 ModCRE Homology model CCCCCCGGGGGGGAGGGGTCCCACAC Region 241-516 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3m_C_1 ModCRE Homology model CCCCCGGGGGGTGGCCGGCAAATCCA Region 241-516 · 1 3D model Open · Scan
TFS_tr_K7ER43_K7ER43_HUMAN:335:488_2i13_A_1 ModCRE Homology model TTTCTATAGCACTCTTAAAAG Region 335-488 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 516 aa
102-231
238-516

Region 102-231 5 PWM

Residues
130 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
5 active PDBs
Templates
2I13, 5EH2, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models

Region 238-516 5 PWM

Residues
279 aa
Domains
PF13465 · Zinc-finger double domain PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 102-2315 models
Actions
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5v3j_E_1 5v3j 102-230 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5v3m_C_1 5v3m 102-230 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:102:230_5wjq_D_1 5wjq 102-230 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:110:208_5eh2_F_1 5eh2 110-208 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:110:231_2i13_A_1 2i13 110-231 View model · PDB
Region 238-5166 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_K7ER43_K7ER43_HUMAN:324:372_1llm_D_1 1llm 324-372 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:238:516_5wjq_D_1 5wjq 238-516 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:239:512_7w1m_H_1 7w1m 239-512 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3j_E_1 5v3j 241-516 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3m_C_1 5v3m 241-516 View model · PDB
Predicted = Low TFS_tr_K7ER43_K7ER43_HUMAN:335:488_2i13_A_1 2i13 335-488 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5wjq 238:516 238 516 P:D · DNA:A,B 53.0% / 66.7% 99 View · PDB TFS_tr_K7ER43_K7ER43_HUMAN:238:516_5wjq_D_1
1 1llm 238:516 324,324 372,372 P:C,D · DNA:A,B 51.0% / 63.3% 56,57 View · PDB DIMER_tr_K7ER43_K7ER43_HUMAN:324:372_1llm_D_1
4 2i13 238:516 335 488 P:A · DNA:C,D 50.6% / 66.9% 100 View · PDB TFS_tr_K7ER43_K7ER43_HUMAN:335:488_2i13_A_1
2 5v3m 238:516 241 516 P:C · DNA:A,B 48.2% / 67.0% 99 View · PDB TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3m_C_1
3 5v3j 238:516 241 516 P:E · DNA:A,B 48.2% / 67.0% 99 View · PDB TFS_tr_K7ER43_K7ER43_HUMAN:241:516_5v3j_E_1
5 7w1m 238:516 239 512 P:H · DNA:F,G 35.3% / 51.6% 85 View · PDB TFS_tr_K7ER43_K7ER43_HUMAN:239:512_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
3-44PF01352KRAB boxNo overlap with loaded model regions
186-208PF00096Zinc finger, C2H2 typeoverlaps 102-231
257-281PF13465Zinc-finger double domainoverlaps 238-516
298-320PF00096Zinc finger, C2H2 typeoverlaps 238-516
326-348PF00096Zinc finger, C2H2 typeoverlaps 238-516
354-376PF00096Zinc finger, C2H2 typeoverlaps 238-516
383-404PF00096Zinc finger, C2H2 typeoverlaps 238-516
410-432PF00096Zinc finger, C2H2 typeoverlaps 238-516
438-460PF00096Zinc finger, C2H2 typeoverlaps 238-516
466-488PF00096Zinc finger, C2H2 typeoverlaps 238-516
494-516PF00096Zinc finger, C2H2 typeoverlaps 238-516