ModCRE DB

Transcription factor

M0QX90 - ZNF649

Zinc finger protein 649

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 477 aa

60 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)56
MotifPredictionSourceDNA bindingSupportLogoActions
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 64.7% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 62.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 62.3% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 62.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 61.1% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 60.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 57.9% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 57.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 57.6% identity Open · Scan
M07725_2.00 NN 70-40% CisBP AAGCACTGTACT 56.9% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 56.2% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 56.1% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 55.8% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 55.2% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 55.1% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 55.0% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.7% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 54.7% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 54.4% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 54.2% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 54.2% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 54.0% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 53.7% identity Open · Scan
M08381_2.00 NN 70-40% CisBP ACATTTTGTCCTCCTAGTCCT 53.6% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 53.4% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 53.4% identity Open · Scan
M08234_2.00 NN 70-40% CisBP GTCAACTTGACTGGGCCA 53.1% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 53.0% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.8% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.6% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 52.5% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 52.5% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 52.3% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 52.3% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 52.2% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 51.7% identity Open · Scan
M06084_2.00 NN 70-40% CisBP AGACCACCCAC 51.6% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.6% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 51.5% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 51.4% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 51.2% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 51.1% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 51.1% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.0% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 51.0% identity Open · Scan
M07633_2.00 NN 70-40% CisBP CTCTCGTTGTGCCTTTGCCAT 50.9% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 50.7% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 50.6% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 50.6% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 50.5% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 50.3% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.0% identity Open · Scan
ModCRE4
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3j_E_1 ModCRE Homology model CCGGGGTGCTTCCCCCACTCCGGGCG Region 154-425 · 1 3D model Open · Scan
TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3m_C_1 ModCRE Homology model CCGACGGGCCCCTCCCGGGCCCCGCC Region 154-425 · 1 3D model Open · Scan
TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5wjq_D_1 ModCRE Homology model CGGCGCGGCGGCCCCCCCTCTTTATCCG Region 154-425 · 1 3D model Open · Scan
TFS_tr_M0QX90_M0QX90_HUMAN:243:396_2i13_A_1 ModCRE Homology model GGGCTGAGGGAGTCTCTAAGT Region 243-396 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 477 aa
154-425

Region 154-425 4 PWM

Residues
272 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 154-4256 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_M0QX90_M0QX90_HUMAN:259:309_1llm_D_1 1llm 259-309 View model · PDB
Predicted = Low TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3j_E_1 5v3j 154-425 View model · PDB
Predicted = Low TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3m_C_1 5v3m 154-425 View model · PDB
Predicted = Low TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5wjq_D_1 5wjq 154-425 View model · PDB
Predicted = Low TFS_tr_M0QX90_M0QX90_HUMAN:162:424_7w1m_H_1 7w1m 162-424 View model · PDB
Predicted = Low TFS_tr_M0QX90_M0QX90_HUMAN:243:396_2i13_A_1 2i13 243-396 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 154:432 243 396 P:A · DNA:C,D 59.1% / 71.4% 100 View · PDB TFS_tr_M0QX90_M0QX90_HUMAN:243:396_2i13_A_1
1 5v3m 154:432 154 425 P:C · DNA:A,B 47.1% / 64.0% 98 View · PDB TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3m_C_1
2 5v3j 154:432 154 425 P:E · DNA:A,B 47.1% / 64.0% 98 View · PDB TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5v3j_E_1
1 1llm 154:432 259,259 309,309 P:C,D · DNA:A,B 47.1% / 54.9% 58,60 View · PDB DIMER_tr_M0QX90_M0QX90_HUMAN:259:309_1llm_D_1
3 5wjq 154:432 154 425 P:D · DNA:A,B 46.3% / 61.8% 96 View · PDB TFS_tr_M0QX90_M0QX90_HUMAN:154:425_5wjq_D_1
5 7w1m 154:432 162 424 P:H · DNA:F,G 37.2% / 48.7% 81 View · PDB TFS_tr_M0QX90_M0QX90_HUMAN:162:424_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
7-48PF01352KRAB boxNo overlap with loaded model regions
178-200PF00096Zinc finger, C2H2 typeoverlaps 154-425
206-228PF00096Zinc finger, C2H2 typeoverlaps 154-425
236-256PF00096Zinc finger, C2H2 typeoverlaps 154-425
262-284PF00096Zinc finger, C2H2 typeoverlaps 154-425
290-312PF00096Zinc finger, C2H2 typeoverlaps 154-425
322-340PF00096Zinc finger, C2H2 typeoverlaps 154-425
346-368PF00096Zinc finger, C2H2 typeoverlaps 154-425
374-396PF00096Zinc finger, C2H2 typeoverlaps 154-425