ModCRE DB

Transcription factor

O14628 - ZNF195

Zinc finger protein 195

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 629 aa

48 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)43
MotifPredictionSourceDNA bindingSupportLogoActions
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 68.2% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 63.5% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 62.3% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 62.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 61.9% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 61.1% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 61.1% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 60.9% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.7% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 60.7% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 60.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 59.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 58.0% identity Open · Scan
M08295_2.00 NN 70-40% CisBP CTGCTGGAATCTCCA 57.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 57.3% identity Open · Scan
M05847_2.00 NN 70-40% CisBP AGACCTACTATGC 57.2% identity Open · Scan
MA1585.1 NN 70-40% JASPAR ATAGTAGGTG 57.2% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 57.1% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 56.5% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 56.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 55.8% identity Open · Scan
M07762_2.00 NN 70-40% CisBP GCCGCGCACAGGCTTCTAGCC 55.8% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 53.6% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 53.5% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 53.5% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 53.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.4% identity Open · Scan
M07685_2.00 NN 70-40% CisBP CTTTCCAGCCAC 53.4% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 53.4% identity Open · Scan
MA1592.1 NN 70-40% JASPAR GGTATGAGTTCTCGCT 53.1% identity Open · Scan
M07633_2.00 NN 70-40% CisBP CTCTCGTTGTGCCTTTGCCAT 52.3% identity Open · Scan
M07620_2.00 NN 70-40% CisBP TTGGATCTGTGGATTCATGTCTTTCAT 52.1% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 52.1% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 51.9% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 51.7% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.4% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 51.3% identity Open · Scan
M08381_2.00 NN 70-40% CisBP ACATTTTGTCCTCCTAGTCCT 50.9% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 50.8% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 50.7% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 50.6% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_O14628_ZN195_HUMAN:223:346_2i13_A_1 ModCRE Homology model AGCTCTTGATCACCAAGTTAA Region 223-346 · 1 3D model Open · Scan
TFS_sp_O14628_ZN195_HUMAN:223:346_5v3j_E_1 ModCRE Homology model AGCCTTTATATACTTAAATTGAA Region 223-346 · 1 3D model Open · Scan
TFS_sp_O14628_ZN195_HUMAN:223:346_5v3m_C_1 ModCRE Homology model AGGGGATGGGGGGGTTGTGGATA Region 223-346 · 1 3D model Open · Scan
TFS_sp_O14628_ZN195_HUMAN:223:346_5wjq_D_1 ModCRE Homology model CGGGGGGGGCCCTGGAGGCC Region 223-346 · 1 3D model Open · Scan
TFS_sp_O14628_ZN195_HUMAN:241:346_5ei9_E_1 ModCRE Homology model CCGGGGACCTCGAGACA Region 241-346 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 629 aa
223-346
351-629

Region 223-346 5 PWM

Residues
124 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
5 active PDBs
Templates
2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models

Region 351-629 0 PWM

Residues
279 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 223-3465 models
Actions
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:223:346_2i13_A_1 2i13 223-346 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:223:346_5v3j_E_1 5v3j 223-346 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:223:346_5v3m_C_1 5v3m 223-346 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:223:346_5wjq_D_1 5wjq 223-346 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:241:346_5ei9_E_1 5ei9 241-346 View model · PDB
Region 351-6296 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_O14628_ZN195_HUMAN:520:569_1llm_D_1 1llm 520-569 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:351:629_5wjq_D_1 5wjq 351-629 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:353:629_5v3j_E_1 5v3j 353-629 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:353:629_5v3m_C_1 5v3m 353-629 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:357:624_7w1m_H_1 7w1m 357-624 View model · PDB
Predicted = Low TFS_sp_O14628_ZN195_HUMAN:475:628_2i13_A_1 2i13 475-628 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 351:629 475 628 P:A · DNA:C,D 56.5% / 71.4% 100 View · PDB TFS_sp_O14628_ZN195_HUMAN:475:628_2i13_A_1
2 5v3m 351:629 353 629 P:C · DNA:A,B 46.6% / 64.6% 100 View · PDB TFS_sp_O14628_ZN195_HUMAN:353:629_5v3m_C_1
3 5v3j 351:629 353 629 P:E · DNA:A,B 46.6% / 64.6% 100 View · PDB TFS_sp_O14628_ZN195_HUMAN:353:629_5v3j_E_1
1 5wjq 351:629 351 629 P:D · DNA:A,B 46.2% / 68.1% 99 View · PDB TFS_sp_O14628_ZN195_HUMAN:351:629_5wjq_D_1
1 1llm 351:629 520,520 569,569 P:C,D · DNA:A,B 44.0% / 66.0% 57,58 View · PDB DIMER_sp_O14628_ZN195_HUMAN:520:569_1llm_D_1
5 7w1m 351:629 357 624 P:H · DNA:F,G 36.6% / 46.9% 83 View · PDB TFS_sp_O14628_ZN195_HUMAN:357:624_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
4-44PF01352KRAB boxNo overlap with loaded model regions
244-266PF00096Zinc finger, C2H2 typeoverlaps 223-346
438-460PF00096Zinc finger, C2H2 typeoverlaps 351-629
466-488PF00096Zinc finger, C2H2 typeoverlaps 351-629
494-516PF00096Zinc finger, C2H2 typeoverlaps 351-629
522-544PF00096Zinc finger, C2H2 typeoverlaps 351-629
550-572PF13912C2H2-type zinc fingeroverlaps 351-629
578-600PF00096Zinc finger, C2H2 typeoverlaps 351-629
606-628PF00096Zinc finger, C2H2 typeoverlaps 351-629