ModCRE DB

Transcription factor

O14862 - AIM2

Interferon-inducible protein AIM2 (Absent in melanoma 2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 343 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_O14862_AIM2_HUMAN:131:339_5z7d_B_1 ModCRE Homology model AGGCGCGCGATGGGAAAT Region 131-339 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:154:338_5z7d_A_1 ModCRE Homology model TTTTAATACGAAA Region 154-338 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:154:338_5z7d_C_1 ModCRE Homology model CCCGCGCGGCAC Region 154-338 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:156:338_8i6k_A_1 ModCRE Homology model CCCTATTTTA Region 156-338 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_A_1 ModCRE Homology model CCCCAGGACA Region 156-341 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_B_1 ModCRE Homology model GCCACAGAAAAA Region 156-341 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_C_1 ModCRE Homology model GGTATTCGG Region 156-341 · 1 3D model Open · Scan
TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_D_1 ModCRE Homology model ATTCCC Region 156-341 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 343 aa
131-341

Region 131-341 8 PWM

Residues
211 aa
Domains
PF02760 · HIN-200/IF120x domain
3D models
8 active PDBs · 5 summary rows
Templates
3RNU, 5Z7D, 8I6K
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 5 summary rows
Region 131-3418 models · 5 summary rows
Actions
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:131:339_5z7d_B_1 5z7d 131-339 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:154:338_5z7d_A_1 5z7d 154-338 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:154:338_5z7d_C_1 5z7d 154-338 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:156:338_8i6k_A_1 8i6k 156-338 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_A_1 3rnu 156-341 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_B_1 3rnu 156-341 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_C_1 3rnu 156-341 View model · PDB
Predicted = Low TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_D_1 3rnu 156-341 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 3rnu 131:341 156 341 P:C · DNA:K,L 49.2% / 65.8% 92 View · PDB TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_C_1
2 3rnu 131:341 156 341 P:B · DNA:K,L 49.2% / 65.8% 92 View · PDB TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_B_1
3 3rnu 131:341 156 341 P:D · DNA:K,L 48.7% / 65.2% 92 View · PDB TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_D_1
4 3rnu 131:341 156 341 P:A · DNA:K,L 48.7% / 65.2% 92 View · PDB TFS_sp_O14862_AIM2_HUMAN:156:341_3rnu_A_1
5 8i6k 131:341 156 338 P:A · DNA:B,C 46.2% / 64.1% 97 View · PDB TFS_sp_O14862_AIM2_HUMAN:156:338_8i6k_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
8-78PF02758PAAD/DAPIN/Pyrin domainNo overlap with loaded model regions
150-317PF02760HIN-200/IF120x domainoverlaps 131-341