ModCRE DB

Transcription factor

O14913

Kruppel-associated box protein

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 447 aa

45 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)39
MotifPredictionSourceDNA bindingSupportLogoActions
M00952_2.00 NN 70-40% CisBP GGATGCTC 66.2% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 62.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 62.6% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 61.4% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 61.4% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 61.4% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 60.7% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 59.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 59.0% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 58.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 58.3% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 58.2% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 56.8% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 56.4% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 56.3% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 55.6% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 53.5% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 53.4% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 53.0% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 52.8% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 52.8% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 51.9% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 51.9% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 51.8% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 51.7% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 51.5% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 51.3% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 51.2% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.0% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 50.9% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 50.5% identity Open · Scan
MA0130.1 NN 70-40% JASPAR ATCCAC 50.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 50.4% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 50.4% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 50.4% identity Open · Scan
M07638_2.00 NN 70-40% CisBP TGCAGCTCCCTGCCC 50.1% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.0% identity Open · Scan
M07593_2.00 NN 70-40% CisBP AGATGAAGTCACCCCTCTTAC 50.0% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_O14913_O14913_HUMAN:304:354_1llm_D_1 ModCRE Homology model TTTCGATCGGGA Region 304-354 · 1 3D model Open · Scan
TFS_tr_O14913_O14913_HUMAN:134:412_5wjq_D_1 ModCRE Homology model GGGGCTCAGGGTTCCCGACCCCCCCCGC Region 134-412 · 1 3D model Open · Scan
TFS_tr_O14913_O14913_HUMAN:136:412_5v3j_E_1 ModCRE Homology model GAGGGGCCCCGGGCCCCCGGGGCCAA Region 136-412 · 1 3D model Open · Scan
TFS_tr_O14913_O14913_HUMAN:136:412_5v3m_C_1 ModCRE Homology model CCCCGAGCACACCCCCCACGCCGGGT Region 136-412 · 1 3D model Open · Scan
TFS_tr_O14913_O14913_HUMAN:137:435_7w1m_H_1 ModCRE Homology model TCGGAGCGCCGAAACAAAACGGCGTACGTACCCATGGCCAAAT Region 137-435 · 1 3D model Open · Scan
TFS_tr_O14913_O14913_HUMAN:174:327_2i13_A_1 ModCRE Homology model ATACGCAAGCTCGTTTCTAGT Region 174-327 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 447 aa
134-435

Region 134-435 6 PWM

Residues
302 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF16622 · zinc-finger C2H2-type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 134-4356 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_O14913_O14913_HUMAN:304:354_1llm_D_1 1llm 304-354 View model · PDB
Predicted = Low TFS_tr_O14913_O14913_HUMAN:134:412_5wjq_D_1 5wjq 134-412 View model · PDB
Predicted = Low TFS_tr_O14913_O14913_HUMAN:136:412_5v3j_E_1 5v3j 136-412 View model · PDB
Predicted = Low TFS_tr_O14913_O14913_HUMAN:136:412_5v3m_C_1 5v3m 136-412 View model · PDB
Predicted = Low TFS_tr_O14913_O14913_HUMAN:137:435_7w1m_H_1 7w1m 137-435 View model · PDB
Predicted = Low TFS_tr_O14913_O14913_HUMAN:174:327_2i13_A_1 2i13 174-327 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 119:436 174 327 P:A · DNA:C,D 54.5% / 59.7% 100 View · PDB TFS_tr_O14913_O14913_HUMAN:174:327_2i13_A_1
1 5v3m 119:436 136 412 P:C · DNA:A,B 50.2% / 67.1% 100 View · PDB TFS_tr_O14913_O14913_HUMAN:136:412_5v3m_C_1
2 5v3j 119:436 136 412 P:E · DNA:A,B 50.2% / 67.1% 100 View · PDB TFS_tr_O14913_O14913_HUMAN:136:412_5v3j_E_1
3 5wjq 119:436 134 412 P:D · DNA:A,B 49.5% / 66.3% 99 View · PDB TFS_tr_O14913_O14913_HUMAN:134:412_5wjq_D_1
1 1llm 119:436 304,304 354,354 P:C,D · DNA:A,B 43.1% / 58.8% 58,60 View · PDB DIMER_tr_O14913_O14913_HUMAN:304:354_1llm_D_1
5 7w1m 119:436 137 435 P:H · DNA:F,G 32.8% / 47.4% 92 View · PDB TFS_tr_O14913_O14913_HUMAN:137:435_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
5-45PF01352KRAB boxNo overlap with loaded model regions
137-159PF00096Zinc finger, C2H2 typeoverlaps 134-435
165-187PF00096Zinc finger, C2H2 typeoverlaps 134-435
193-215PF00096Zinc finger, C2H2 typeoverlaps 134-435
221-243PF00096Zinc finger, C2H2 typeoverlaps 134-435
250-268PF00096Zinc finger, C2H2 typeoverlaps 134-435
277-299PF00096Zinc finger, C2H2 typeoverlaps 134-435
305-327PF00096Zinc finger, C2H2 typeoverlaps 134-435
333-355PF16622zinc-finger C2H2-typeoverlaps 134-435
361-383PF00096Zinc finger, C2H2 typeoverlaps 134-435