ModCRE DB

Transcription factor

O15015 - ZNF646

Zinc finger protein 646

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1832 aa

6 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_O15015_ZN646_HUMAN:1201:1251_1llm_D_1 ModCRE Homology model TTCGCGCGCGAA Region 1201-1251 · 1 3D model Open · Scan
TFS_sp_O15015_ZN646_HUMAN:1050:1101_4gzn_C_1 ModCRE Homology model CCAGCAGAAT Region 1050-1101 · 1 3D model Open · Scan
TFS_sp_O15015_ZN646_HUMAN:1050:1101_4m9v_C_1 ModCRE Homology model CTTGCAGATT Region 1050-1101 · 1 3D model Open · Scan
TFS_sp_O15015_ZN646_HUMAN:463:514_1f2i_G_1 ModCRE Homology model TGTCGCGCGGT Region 463-514 · 1 3D model Open · Scan
TFS_sp_O15015_ZN646_HUMAN:463:514_1f2i_H_1 ModCRE Homology model CCGCGCGAAA Region 463-514 · 1 3D model Open · Scan
TFS_sp_O15015_ZN646_HUMAN:619:677_5yj3_C_1 ModCRE Homology model AATAAA Region 619-677 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1832 aa
463-514
619-677
1050-1101
1201-1348
1533-1783

Region 463-514 2 PWM

Residues
52 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
2 active PDBs
Templates
1F2I
Sources
Predicted = Low
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Region 619-677 1 PWM

Residues
59 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
5YJ3
Sources
Predicted = Low
Scan this region Show models

Region 1050-1101 2 PWM

Residues
52 aa
Domains
PF00096 · Zinc finger, C2H2 type
3D models
2 active PDBs
Templates
4GZN, 4M9V
Sources
Predicted = Low
Scan this region Show models

Region 1201-1348 1 PWM

Residues
148 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
2 active PDBs · 2 summary rows
Templates
1LLM, 2I13
Sources
Predicted = Low
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Region 1533-1783 0 PWM

Residues
251 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger
3D models
4 active PDBs · 4 summary rows
Templates
5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 463-5142 models
Actions
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:463:514_1f2i_G_1 1f2i 463-514 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:463:514_1f2i_H_1 1f2i 463-514 View model · PDB
Region 619-6771 model
Actions
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:619:677_5yj3_C_1 5yj3 619-677 View model · PDB
Region 1050-11012 models
Actions
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1050:1101_4gzn_C_1 4gzn 1050-1101 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1050:1101_4m9v_C_1 4m9v 1050-1101 View model · PDB
Region 1201-13482 models · 2 summary rows
Actions
Predicted = Low DIMER_sp_O15015_ZN646_HUMAN:1201:1251_1llm_D_1 1llm 1201-1251 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1201:1348_2i13_A_1 2i13 1201-1348 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2i13 1198:1348 1201 1348 P:A · DNA:C,D 32.7% / 52.0% 89 View · PDB TFS_sp_O15015_ZN646_HUMAN:1201:1348_2i13_A_1
1 1llm 1198:1348 1201,1201 1251,1251 P:C,D · DNA:A,B 30.8% / 48.1% 58,60 View · PDB DIMER_sp_O15015_ZN646_HUMAN:1201:1251_1llm_D_1
Region 1533-17834 models · 4 summary rows
Actions
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1533:1783_5v3j_E_1 5v3j 1533-1783 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1533:1783_5v3m_C_1 5v3m 1533-1783 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1533:1783_5wjq_D_1 5wjq 1533-1783 View model · PDB
Predicted = Low TFS_sp_O15015_ZN646_HUMAN:1674:1783_5ei9_E_1 5ei9 1674-1783 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 1198:1348 1674 1783 P:E · DNA:A,B 36.0% / 50.5% 98 View · PDB TFS_sp_O15015_ZN646_HUMAN:1674:1783_5ei9_E_1
2 5v3m 1198:1348 1533 1783 P:C · DNA:A,B 28.6% / 41.6% 87 View · PDB TFS_sp_O15015_ZN646_HUMAN:1533:1783_5v3m_C_1
3 5v3j 1198:1348 1533 1783 P:E · DNA:A,B 28.6% / 41.6% 87 View · PDB TFS_sp_O15015_ZN646_HUMAN:1533:1783_5v3j_E_1
4 5wjq 1198:1348 1533 1783 P:D · DNA:A,B 28.0% / 41.7% 86 View · PDB TFS_sp_O15015_ZN646_HUMAN:1533:1783_5wjq_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
48-70PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
75-97PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
239-261PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
294-316PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
374-396PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
465-487PF00096Zinc finger, C2H2 typeoverlaps 463-514
492-514PF00096Zinc finger, C2H2 typeoverlaps 463-514
617-639PF00096Zinc finger, C2H2 typeoverlaps 619-677
848-871PF13912C2H2-type zinc fingerNo overlap with loaded model regions
1052-1074PF00096Zinc finger, C2H2 typeoverlaps 1050-1101
1203-1225PF00096Zinc finger, C2H2 typeoverlaps 1201-1348
1258-1280PF00096Zinc finger, C2H2 typeoverlaps 1201-1348
1299-1321PF00096Zinc finger, C2H2 typeoverlaps 1201-1348
1326-1348PF00096Zinc finger, C2H2 typeoverlaps 1201-1348
1365-1386PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
1585-1607PF00096Zinc finger, C2H2 typeoverlaps 1533-1783
1677-1699PF00096Zinc finger, C2H2 typeoverlaps 1533-1783
1731-1752PF13912C2H2-type zinc fingeroverlaps 1533-1783