Transcription factor

O15516 - CLOCK

Circadian locomoter output cycles protein kaput (hCLOCK) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 8) (bHLHe8)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 846 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8

Motif	Prediction	Source	DNA binding	Support	Actions
MA0819.1	Known	JASPAR	AACACGTGTT	Direct PWM	Open · Scan
MA0819.2	Known	JASPAR	AAACACGTGC	Direct PWM	Open · Scan
MA0819.3	Known	JASPAR	ACACGTG	Direct PWM	Open · Scan
M02789_2.00	Known	CisBP	AACACGTGTT	Direct PWM	Open · Scan
M04129_2.00	Known	CisBP	GCCACGTGCC	Direct PWM	Open · Scan
M04130_2.00	Known	CisBP	AACACATGTC	Direct PWM	Open · Scan
M08728_2.00	Known	CisBP	TGTTCACGTGTCTG	Direct PWM	Open · Scan
CLOCK_HUMAN.H11MO.0.C	Known	HOCOMOCO	CAGACACGTGAACA	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 846 aa

31-89

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 31-891 model

				Actions
Predicted = Low	DIMER_O15516:31:89_4h10_B_1	4h10	31-89	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
35-83	PF00010	Helix-loop-helix DNA-binding domain	overlaps 31-89
110-177	PF00989	PAS fold	No overlap with loaded model regions
274-377	PF14598	PAS domain	No overlap with loaded model regions