ModCRE DB

Transcription factor

O15522 - NKX2-8

Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 239 aa

10 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known10
MotifPredictionSourceDNA bindingSupportLogoActions
MA0673.1 Known JASPAR CCACTTGAA Direct PWM Open · Scan
MA0673.2 Known JASPAR CCACTTGA Direct PWM Open · Scan
M00301_2.00 Known CisBP TTAAGTGC Direct PWM Open · Scan
M00302_2.00 Known CisBP TTAAGTGC Direct PWM Open · Scan
M05149_2.00 Known CisBP CTCAAGTGGT Direct PWM Open · Scan
M05150_2.00 Known CisBP GCAATAACGACATC Direct PWM Open · Scan
M05151_2.00 Known CisBP CTCAAGTGGT Direct PWM Open · Scan
M05152_2.00 Known CisBP TTCAACGAG Direct PWM Open · Scan
M09145_2.00 Known CisBP TTCAAGGAC Direct PWM Open · Scan
NKX28_HUMAN.H11MO.0.C Known HOCOMOCO TTCAAGGAC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 239 aa
84-140

Region 84-140 0 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
3RKQ
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 84-1401 model
Actions
Predicted = Low DIMER_O15522:84:140_3rkq_A_1 3rkq 84-140 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
85-141PF00046Homeodomainoverlaps 84-140