ModCRE DB

Transcription factor

O43151 - TET3

Methylcytosine dioxygenase TET3 (EC 1.14.11.80)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1795 aa

6 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_O43151_TET3_HUMAN:72:89_1hcq_B_1 ModCRE Homology model GATTTAAAT Region 72-89 · 1 3D model Open · Scan
TFS_sp_O43151_TET3_HUMAN:52:94_5w9s_C_1 ModCRE Homology model CCCCCGGGGGGC Region 52-94 · 1 3D model Open · Scan
TFS_sp_O43151_TET3_HUMAN:53:95_6asd_C_1 ModCRE Homology model CGCCCCCCCCGC Region 53-95 · 1 3D model Open · Scan
TFS_sp_O43151_TET3_HUMAN:55:79_3qmg_A_1 ModCRE Homology model GGCCCCCGGGGC Region 55-79 · 1 3D model Open · Scan
TFS_sp_O43151_TET3_HUMAN:55:79_3qmh_A_1 ModCRE Homology model CGCCCGCGCGGG Region 55-79 · 1 3D model Open · Scan
TFS_sp_O43151_TET3_HUMAN:55:79_3qmi_A_1 ModCRE Homology model TAGCCCGGGGGG Region 55-79 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1795 aa
52-95

Region 52-95 6 PWM

Residues
44 aa
Domains
PF02008 · CXXC zinc finger domain
3D models
6 active PDBs · 6 summary rows
Templates
1HCQ, 3QMG, 3QMH, 3QMI, 5W9S, 6ASD
Sources
Predicted = Low
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 52-956 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_O43151_TET3_HUMAN:72:89_1hcq_B_1 1hcq 72-89 View model · PDB
Predicted = Low TFS_sp_O43151_TET3_HUMAN:52:94_5w9s_C_1 5w9s 52-94 View model · PDB
Predicted = Low TFS_sp_O43151_TET3_HUMAN:53:95_6asd_C_1 6asd 53-95 View model · PDB
Predicted = Low TFS_sp_O43151_TET3_HUMAN:55:79_3qmg_A_1 3qmg 55-79 View model · PDB
Predicted = Low TFS_sp_O43151_TET3_HUMAN:55:79_3qmh_A_1 3qmh 55-79 View model · PDB
Predicted = Low TFS_sp_O43151_TET3_HUMAN:55:79_3qmi_A_1 3qmi 55-79 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5w9s 52:95 52 94 P:C · DNA:A,B 72.7% / 77.3% 97 View · PDB TFS_sp_O43151_TET3_HUMAN:52:94_5w9s_C_1
2 6asd 52:95 53 95 P:C · DNA:A,B 70.5% / 79.5% 97 View · PDB TFS_sp_O43151_TET3_HUMAN:53:95_6asd_C_1
1 1hcq 52:95 72,72 89,89 P:A,B · DNA:C,D 57.9% / 63.2% 24,25 View · PDB DIMER_sp_O43151_TET3_HUMAN:72:89_1hcq_B_1
3 3qmh 52:95 55 79 P:A · DNA:B,C 48.0% / 64.0% 47 View · PDB TFS_sp_O43151_TET3_HUMAN:55:79_3qmh_A_1
4 3qmi 52:95 55 79 P:A · DNA:B,C 48.0% / 64.0% 48 View · PDB TFS_sp_O43151_TET3_HUMAN:55:79_3qmi_A_1
5 3qmg 52:95 55 79 P:A · DNA:B,C 48.0% / 64.0% 48 View · PDB TFS_sp_O43151_TET3_HUMAN:55:79_3qmg_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
51-89PF02008CXXC zinc finger domainoverlaps 52-95
985-1697PF12851Oxygenase domain of the 2OGFeDO superfamilyNo overlap with loaded model regions