ModCRE DB

Transcription factor

O43245 - p65

Protein p65

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 614 aa

17 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)6
MotifPredictionSourceDNA bindingSupportLogoActions
MA0258.1 NN 70-40% JASPAR CAAGGTCACGGTGACCTG 54.4% identity Open · Scan
M09309_2.00 NN 70-40% CisBP AGGTCAGGGTGACCT 52.5% identity Open · Scan
MA0112.1 NN 70-40% JASPAR CCAGGTCACCGTGACCCC 52.5% identity Open · Scan
M09296_2.00 NN 70-40% CisBP TCAAGGTCA 50.7% identity Open · Scan
MA0141.3 NN 70-40% JASPAR TCAAGGTCATA 50.7% identity Open · Scan
MA0643.1 NN 70-40% JASPAR TCAAGGTCAT 50.7% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_O43245_O43245_HUMAN:302:361_4oln_A_1 ModCRE Homology model TAAGGTCATTTTGACCTTT Region 302-361 · 1 3D model Open · Scan
DIMER_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1 ModCRE Homology model CAGGTCATAGGTCAAAG Region 302-363 · 1 3D model Open · Scan
DIMER_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1 ModCRE Homology model CAGGTCATTGTGACCTG Region 303-361 · 1 3D model Open · Scan
DIMER_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1 ModCRE Homology model CAGGTCACTGTGACCTG Region 303-361 · 1 3D model Open · Scan
DIMER_tr_O43245_O43245_HUMAN:303:368_6bse_A_1 ModCRE Homology model ATATAGGTAAATGTG Region 303-368 · 1 3D model Open · Scan
DIMER_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1 ModCRE Homology model CAAGTTGACCTATGG Region 303-368 · 1 3D model Open · Scan
TFS_tr_O43245_O43245_HUMAN:302:358_1lo1_A_1 ModCRE Homology model GGACAAGGGTCAT Region 302-358 · 1 3D model Open · Scan
TFS_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1 ModCRE Homology model ATTTGACCTATGACCTG Region 302-363 · 1 3D model Open · Scan
TFS_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1 ModCRE Homology model CAGGTCACAATGACCTG Region 303-361 · 1 3D model Open · Scan
TFS_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1 ModCRE Homology model CAGGTCAAATTGACCTG Region 303-361 · 1 3D model Open · Scan
TFS_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1 ModCRE Homology model ACATAGGTCAAATTG Region 303-368 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 614 aa
302-368

Region 302-368 11 PWM

Residues
67 aa
Domains
PF00105 · Double treble clef zinc finger, C4 type
3D models
11 active PDBs · 10 summary rows
Templates
1HCQ, 1LO1, 4AA6, 4OLN, 6BSE, 6BSF, 8IFO
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 10 summary rows
Region 302-36811 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:302:361_4oln_A_1 4oln 302-361 View model · PDB
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1 8ifo 302-363 View model · PDB
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1 1hcq 303-361 View model · PDB
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1 4aa6 303-361 View model · PDB
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:303:368_6bse_A_1 6bse 303-368 View model · PDB
Predicted = Low DIMER_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1 6bsf 303-368 View model · PDB
Predicted = Low TFS_tr_O43245_O43245_HUMAN:302:358_1lo1_A_1 1lo1 302-358 View model · PDB
Predicted = Low TFS_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1 8ifo 302-363 View model · PDB
Predicted = Low TFS_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1 1hcq 303-361 View model · PDB
Predicted = Low TFS_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1 4aa6 303-361 View model · PDB
Predicted = Low TFS_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1 6bsf 303-368 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 4aa6 296:375 303,303 361,361 P:A,B · DNA:C,D 57.4% / 60.7% 83,84 View · PDB DIMER_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1
1 4aa6 296:375 303,303 361,361 P:A,B · DNA:C,D 57.4% / 60.7% 83,84 View · PDB TFS_tr_O43245_O43245_HUMAN:303:361_4aa6_B_1
2 1hcq 296:375 303,303 361,361 P:A,B · DNA:C,D 57.4% / 60.7% 79,83 View · PDB DIMER_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1
2 1hcq 296:375 303,303 361,361 P:A,B · DNA:C,D 57.4% / 60.7% 79,83 View · PDB TFS_tr_O43245_O43245_HUMAN:303:361_1hcq_B_1
4 1lo1 296:375 302 358 P:A · DNA:B,C 52.5% / 66.1% 63 View · PDB TFS_tr_O43245_O43245_HUMAN:302:358_1lo1_A_1
3 8ifo 296:375 302,302 363,363 P:A,B · DNA:C,D 50.8% / 66.2% 81,77 View · PDB DIMER_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1
3 8ifo 296:375 302,302 363,363 P:A,B · DNA:C,D 50.8% / 66.2% 81,77 View · PDB TFS_tr_O43245_O43245_HUMAN:302:363_8ifo_A_1
4 6bsf 296:375 303,303 368,368 P:A,B · DNA:C,D 44.9% / 59.4% 91,90 View · PDB DIMER_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1
5 6bse 296:375 303,303 368,368 P:A,B · DNA:C,D 44.9% / 59.4% 90,91 View · PDB DIMER_tr_O43245_O43245_HUMAN:303:368_6bse_A_1
5 6bsf 296:375 303,303 368,368 P:A,B · DNA:C,D 44.9% / 59.4% 91,90 View · PDB TFS_tr_O43245_O43245_HUMAN:303:368_6bsf_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
304-363PF00105Double treble clef zinc finger, C4 typeoverlaps 302-368
484-547PF21229TdIF1, C-terminalNo overlap with loaded model regions