ModCRE DB

Transcription factor

O43524 - FOXO3

Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 673 aa

10 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known10
MotifPredictionSourceDNA bindingSupportLogoActions
MA0157.1 Known JASPAR TGTAAACA Direct PWM Open · Scan
MA0157.2 Known JASPAR GTAAACAA Direct PWM Open · Scan
M03019_2.00 Known CisBP GTAAACATGTTTAC Direct PWM Open · Scan
M03020_2.00 Known CisBP GTAAACAA Direct PWM Open · Scan
M03021_2.00 Known CisBP TTTCCCCACAC Direct PWM Open · Scan
M04813_2.00 Known CisBP TTCCCCACACG Direct PWM Open · Scan
M04814_2.00 Known CisBP TTCCCCACACG Direct PWM Open · Scan
M09087_2.00 Known CisBP TGTAAACAAG Direct PWM Open · Scan
M10537_2.00 Known CisBP TATGTAAACAACAA Direct PWM Open · Scan
FOXO3_HUMAN.H11MO.0.B Known HOCOMOCO CTTGTTTACA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 673 aa
157-242

Region 157-242 0 PWM

Residues
86 aa
Domains
PF00250 · Forkhead domain
3D models
1 active PDB
Templates
5DUI
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 157-2421 model
Actions
Predicted = Low DIMER_O43524:157:242_5dui_A_1 5dui 157-242 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
159-240PF00250Forkhead domainoverlaps 157-242
433-511PF16675KIX-binding domain of forkhead box O, CR2No overlap with loaded model regions
604-644PF16676Transactivation domain of FOXO protein familyNo overlap with loaded model regions