Transcription factor

O43918 - AIRE

Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 545 aa

3 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M09375_2.00	Known	CisBP	TTAACCAATAAAACCAAT	Direct PWM		Open · Scan
AIRE_HUMAN.H11MO.0.C	Known	HOCOMOCO	ATTGGTTATATTGGTTAA	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M01680_2.00	NN 70-40%	CisBP	AAAATAAA	50.7% identity		Open · Scan

ModCRE0

No generated PWM in this category.

None of the 6 assessable structural models contains a protein–DNA non-hydrogen atom contact within 4.5 Å.

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

6 active PDB models

Source	Model	Template	Residues modeled	Actions
Predicted = Low	o43918.af3.0	-	Full sequence	View model · PDB
Predicted = Low	o43918.af3.1	-	Full sequence	View model · PDB
Predicted = Low	o43918.af3.2	-	Full sequence	View model · PDB
Predicted = Low	o43918.af3.3	-	Full sequence	View model · PDB
Predicted = Low	o43918.af3.4	-	Full sequence	View model · PDB
Predicted = Low	o43918.af3.5	-	Full sequence	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.