ModCRE DB

Transcription factor

O60304 - ZNF500

Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 480 aa

123 Generated PWM 10 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)114
MotifPredictionSourceDNA bindingSupportLogoActions
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.9% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.9% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 64.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 64.7% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 63.6% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 63.6% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 62.5% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 62.5% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 60.9% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 60.8% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 60.7% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 60.4% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 60.4% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 60.1% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 59.0% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 59.0% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 58.3% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 58.1% identity Open · Scan
M00149_2.00 NN 70-40% CisBP CGTACGCC 57.9% identity Open · Scan
M00764_2.00 NN 70-40% CisBP GTCTACAC 57.8% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 57.3% identity Open · Scan
M07598_2.00 NN 70-40% CisBP CTGACAATACCAAGTGTTGAC 57.1% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 56.9% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 56.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 56.8% identity Open · Scan
MA1597.1 NN 70-40% JASPAR CCCAGGGAAGCCATTTC 56.6% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 56.2% identity Open · Scan
M00769_2.00 NN 70-40% CisBP ACTCCCCC 56.1% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 56.0% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 55.9% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 55.7% identity Open · Scan
M08342_2.00 NN 70-40% CisBP GCTCTGCCTCCCTCT 55.6% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 55.5% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 55.3% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 55.2% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 55.2% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 55.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 55.2% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 55.2% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 55.2% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 54.9% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 54.9% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 54.6% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 54.6% identity Open · Scan
M07623_2.00 NN 70-40% CisBP GTCTAATAGAGCTGGGCTGCA 54.6% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 54.6% identity Open · Scan
M08399_2.00 NN 70-40% CisBP TACTCTGGGGCCACATGACTC 54.6% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 54.6% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 54.5% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 54.5% identity Open · Scan
M08279_2.00 NN 70-40% CisBP CCTCCCTCC 54.1% identity Open · Scan
M07703_2.00 NN 70-40% CisBP CCGACGG 54.0% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 53.9% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 53.9% identity Open · Scan
MA0747.1 NN 70-40% JASPAR GCCACGCCCACT 53.7% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 53.6% identity Open · Scan
M07645_2.00 NN 70-40% CisBP CTCCTT 53.4% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 53.2% identity Open · Scan
M08239_2.00 NN 70-40% CisBP GGGCCGCTCTAGGCTGCCGG 53.2% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.1% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 53.1% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 53.1% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 53.1% identity Open · Scan
M07693_2.00 NN 70-40% CisBP CTCCTGTGTGTGCCTTGGCTG 53.1% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 53.1% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 53.0% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 52.9% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 52.8% identity Open · Scan
M07717_2.00 NN 70-40% CisBP GGCTCCGCCCCC 52.8% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 52.8% identity Open · Scan
M00765_2.00 NN 70-40% CisBP CCCGCCCCC 52.6% identity Open · Scan
M05859_2.00 NN 70-40% CisBP GGCCACGCCCACT 52.6% identity Open · Scan
MA0079.1 NN 70-40% JASPAR GGGGCGGGGT 52.6% identity Open · Scan
MA0685.1 NN 70-40% JASPAR TAAGCCACGCCCCCTTT 52.6% identity Open · Scan
M03682_2.00 NN 70-40% CisBP ACGCCACGCCCAGT 52.5% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 52.5% identity Open · Scan
MA1564.1 NN 70-40% JASPAR GCCACGCCCCCC 52.5% identity Open · Scan
MA1580.1 NN 70-40% JASPAR TGTACAGTAT 52.3% identity Open · Scan
M07701_2.00 NN 70-40% CisBP CCTGGGCTAGGCCCTGGC 52.2% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 52.0% identity Open · Scan
MA1588.1 NN 70-40% JASPAR GAATTCTTGGTTGAC 52.0% identity Open · Scan
MA1594.1 NN 70-40% JASPAR AGGGGACATCACTACAGATCCCAC 52.0% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 51.8% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 51.8% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 51.8% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 51.7% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 51.7% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 51.7% identity Open · Scan
M07720_2.00 NN 70-40% CisBP TGTGTGTGTGGGCATGTGTGTGTGCGAGT 51.7% identity Open · Scan
M08386_2.00 NN 70-40% CisBP GCCTTAAAAGCTCAGCAC 51.7% identity Open · Scan
M04610_2.00 NN 70-40% CisBP CGGCGACGCGAACAC 51.6% identity Open · Scan
M07593_2.00 NN 70-40% CisBP AGATGAAGTCACCCCTCTTAC 51.6% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 51.6% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 51.3% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.0% identity Open · Scan
M00774_2.00 NN 70-40% CisBP TTAGTATACACAAGT 50.9% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M07731_2.00 NN 70-40% CisBP TTTCCCAGCAGCAACAGCACCGCCCCCCCC 50.7% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 50.7% identity Open · Scan
M04615_2.00 NN 70-40% CisBP CTCGATCGAAGGGCACAGTCATT 50.6% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 50.6% identity Open · Scan
M07633_2.00 NN 70-40% CisBP CTCTCGTTGTGCCTTTGCCAT 50.3% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 50.3% identity Open · Scan
M07688_2.00 NN 70-40% CisBP GAGCCCCAAGCA 50.3% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 50.3% identity Open · Scan
M08358_2.00 NN 70-40% CisBP CCCTCCCCCTCC 50.3% identity Open · Scan
M01192_2.00 NN 70-40% CisBP CCCCCTGA 50.0% identity Open · Scan
M06466_2.00 NN 70-40% CisBP TCCGCCCCCT 50.0% identity Open · Scan
M07662_2.00 NN 70-40% CisBP CCTGTGTCCTCCCTGGTCCCC 50.0% identity Open · Scan
M07740_2.00 NN 70-40% CisBP TCCTGATTCCACACTCAAACATAACTTT 50.0% identity Open · Scan
M08246_2.00 NN 70-40% CisBP GCCCCACCCA 50.0% identity Open · Scan
MA1511.1 NN 70-40% JASPAR GCCACACCCCC 50.0% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_O60304_ZN500_HUMAN:318:459_2i13_A_1 ModCRE Homology model ATTAACTCTCTAACTCTAACC Region 318-459 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:318:459_5v3j_E_1 ModCRE Homology model GGGTCGGGGGGGGGGGGCCCCAA Region 318-459 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:318:459_5v3m_C_1 ModCRE Homology model GGGGGGTCCCCGGCGGGCCCCC Region 318-459 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:318:461_5wjq_D_1 ModCRE Homology model TTGGGGGGGGGGGGCGGGGCCCC Region 318-461 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:322:432_5egb_A_1 ModCRE Homology model CCGGGACCAGGGGGGCGG Region 322-432 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:322:432_5ei9_E_1 ModCRE Homology model CCGGGGGGGGGGGGACC Region 322-432 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:324:432_5eh2_F_1 ModCRE Homology model GGGGGGAGAGGGGGTCCCC Region 324-432 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:350:459_2jp9_A_1 ModCRE Homology model GGGGGGGGAGGGTTCGG Region 350-459 · 1 3D model Open · Scan
TFS_sp_O60304_ZN500_HUMAN:350:459_2jpa_A_1 ModCRE Homology model GGGGGCCACCGGCT Region 350-459 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 480 aa
318-461

Region 318-461 9 PWM

Residues
144 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
10 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 2JP9, 2JPA, 5EGB, 5EH2, 5EI9, 5V3J, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
10 active PDB models 6 summary rows
Region 318-46110 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_O60304_ZN500_HUMAN:407:456_1llm_D_1 1llm 407-456 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:318:459_2i13_A_1 2i13 318-459 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:318:459_5v3j_E_1 5v3j 318-459 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:318:459_5v3m_C_1 5v3m 318-459 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:318:461_5wjq_D_1 5wjq 318-461 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:322:432_5egb_A_1 5egb 322-432 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:322:432_5ei9_E_1 5ei9 322-432 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:324:432_5eh2_F_1 5eh2 324-432 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:350:459_2jp9_A_1 2jp9 350-459 View model · PDB
Predicted = Low TFS_sp_O60304_ZN500_HUMAN:350:459_2jpa_A_1 2jpa 350-459 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2i13 318:461 318 459 P:A · DNA:C,D 62.0% / 71.8% 92 View · PDB TFS_sp_O60304_ZN500_HUMAN:318:459_2i13_A_1
5 5ei9 318:461 322 432 P:E · DNA:A,B 60.4% / 75.7% 100 View · PDB TFS_sp_O60304_ZN500_HUMAN:322:432_5ei9_E_1
3 5v3m 318:461 318 459 P:C · DNA:A,B 52.1% / 68.3% 51 View · PDB TFS_sp_O60304_ZN500_HUMAN:318:459_5v3m_C_1
4 5v3j 318:461 318 459 P:E · DNA:A,B 52.1% / 68.3% 51 View · PDB TFS_sp_O60304_ZN500_HUMAN:318:459_5v3j_E_1
2 5wjq 318:461 318 461 P:D · DNA:A,B 51.4% / 67.4% 51 View · PDB TFS_sp_O60304_ZN500_HUMAN:318:461_5wjq_D_1
1 1llm 318:461 407,407 456,456 P:C,D · DNA:A,B 44.0% / 62.0% 57,58 View · PDB DIMER_sp_O60304_ZN500_HUMAN:407:456_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
46-134PF02023SCAN domainNo overlap with loaded model regions
223-247PF01352KRAB boxNo overlap with loaded model regions
325-347PF00096Zinc finger, C2H2 typeoverlaps 318-461
353-375PF00096Zinc finger, C2H2 typeoverlaps 318-461
381-403PF00096Zinc finger, C2H2 typeoverlaps 318-461
409-431PF00096Zinc finger, C2H2 typeoverlaps 318-461
437-459PF00096Zinc finger, C2H2 typeoverlaps 318-461