ModCRE DB

Transcription factor

O60315 - ZEB2

Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1214 aa

43 Generated PWM 17 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)29
MotifPredictionSourceDNA bindingSupportLogoActions
M07842_2.00 NN 70-40% CisBP CTCACCTG 60.6% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 56.8% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 55.8% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 53.6% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 53.3% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 53.0% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.7% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 52.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 52.1% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.1% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 51.5% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 51.4% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 51.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 51.3% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 51.3% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.2% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 50.7% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.7% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.6% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 50.6% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 50.6% identity Open · Scan
M01468_2.00 NN 70-40% CisBP TTACCCCTGA 50.0% identity Open · Scan
M01883_2.00 NN 70-40% CisBP TGCCCCTGA 50.0% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 50.0% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 50.0% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.0% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.0% identity Open · Scan
MA0038.1 NN 70-40% JASPAR CAAATCACTG 50.0% identity Open · Scan
MA0038.2 NN 70-40% JASPAR CAAATCACTGCA 50.0% identity Open · Scan
ModCRE14
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_O60315_ZEB2_HUMAN:344:374_3coq_B_1 ModCRE Homology model AATAACTGTTAA Region 344-374 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:1004:1078_5keb_A_1 ModCRE Homology model GGGGGCGTGC Region 1004-1078 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:213:332_5kkq_A_1 ModCRE Homology model TTCCACCAACTAGCCGG Region 213-332 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:213:332_5t00_A_1 ModCRE Homology model TCTCCACGCGCTGCCGG Region 213-332 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:213:332_5t0u_A_1 ModCRE Homology model TTCCCCTAGCGCTGCGCGATCC Region 213-332 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1050_1f2i_G_1 ModCRE Homology model GGGTAATTACC Region 999-1050 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1050_1f2i_H_1 ModCRE Homology model AGGAACCACCA Region 999-1050 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1052_4gzn_C_1 ModCRE Homology model CCCTGGCCCC Region 999-1052 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1052_4m9v_C_1 ModCRE Homology model CCTCAGCCCC Region 999-1052 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1g_A_1 ModCRE Homology model GGCGGCCCCC Region 999-1073 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1h_A_1 ModCRE Homology model CCGCGCCCCC Region 999-1073 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1i_A_1 ModCRE Homology model ACCGGCCCAC Region 999-1073 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1j_A_1 ModCRE Homology model ACCCGGCCCC Region 999-1073 · 1 3D model Open · Scan
TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1k_A_1 ModCRE Homology model CCCGGGCCCC Region 999-1073 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1214 aa
213-332
344-374
999-1078

Region 213-332 3 PWM

Residues
120 aa
Domains
PF05605 · Drought induced 19 protein (Di19), zinc-binding PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
5 active PDBs
Templates
5KKQ, 5T00, 5T0U, 5YEF
Sources
Predicted = Low
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Region 344-374 1 PWM

Residues
31 aa
Domains
No overlapping PFAM annotation recorded
3D models
1 active PDB
Templates
3COQ
Sources
Predicted = Low
Scan this region Show models

Region 999-1078 10 PWM

Residues
80 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1A1G, 1A1H, 1A1I, 1A1J, 1A1K, 1F2I, 1LLM, 4GZN, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
17 active PDB models 6 summary rows
Region 213-3325 models
Actions
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:213:332_5kkq_A_1 5kkq 213-332 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:213:332_5t00_A_1 5t00 213-332 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:213:332_5t0u_A_1 5t0u 213-332 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:213:332_5yef_B_1 5yef 213-332 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:213:332_5yef_J_1 5yef 213-332 View model · PDB
Region 344-3741 model
Actions
Predicted = Low DIMER_sp_O60315_ZEB2_HUMAN:344:374_3coq_B_1 3coq 344-374 View model · PDB
Region 999-107811 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_O60315_ZEB2_HUMAN:1025:1073_1llm_D_1 1llm 1025-1073 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:1004:1078_5keb_A_1 5keb 1004-1078 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1050_1f2i_G_1 1f2i 999-1050 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1050_1f2i_H_1 1f2i 999-1050 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1052_4gzn_C_1 4gzn 999-1052 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1052_4m9v_C_1 4m9v 999-1052 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1g_A_1 1a1g 999-1073 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1h_A_1 1a1h 999-1073 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1i_A_1 1a1i 999-1073 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1j_A_1 1a1j 999-1073 View model · PDB
Predicted = Low TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1k_A_1 1a1k 999-1073 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 1a1h 982:1079 999 1073 P:A · DNA:B,C 46.8% / 63.6% 88 View · PDB TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1h_A_1
5 1a1g 982:1079 999 1073 P:A · DNA:B,C 46.8% / 63.6% 89 View · PDB TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1g_A_1
1 1a1j 982:1079 999 1073 P:A · DNA:B,C 45.5% / 63.6% 89 View · PDB TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1j_A_1
2 1a1k 982:1079 999 1073 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1k_A_1
3 1a1i 982:1079 999 1073 P:A · DNA:B,C 45.5% / 63.6% 88 View · PDB TFS_sp_O60315_ZEB2_HUMAN:999:1073_1a1i_A_1
1 1llm 982:1079 1025,1025 1073,1073 P:C,D · DNA:A,B 44.9% / 63.3% 56,57 View · PDB DIMER_sp_O60315_ZEB2_HUMAN:1025:1073_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
211-262PF05605Drought induced 19 protein (Di19), zinc-bindingoverlaps 213-332
282-304PF00096Zinc finger, C2H2 typeoverlaps 213-332
310-330PF00096Zinc finger, C2H2 typeoverlaps 213-332
999-1021PF00096Zinc finger, C2H2 typeoverlaps 999-1078
1055-1075PF00096Zinc finger, C2H2 typeoverlaps 999-1078