ModCRE DB

Transcription factor

O60393 - NOBOX

Homeobox protein NOBOX

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 691 aa

16 Generated PWM 20 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3
MotifPredictionSourceDNA bindingSupportLogoActions
M02084_2.00 Known CisBP CTTAATTGGC Direct PWM Open · Scan
M09135_2.00 Known CisBP CTAATTGGT Direct PWM Open · Scan
NOBOX_HUMAN.H11MO.0.C Known HOCOMOCO CTAATTGGT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
MA0125.1 NN 70-40% JASPAR TAATTGGT 58.8% identity Open · Scan
M02103_2.00 NN 70-40% CisBP AGGTGTAAA 52.9% identity Open · Scan
M02221_2.00 NN 70-40% CisBP CTTAATTGGT 50.9% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_O60393_NOBOX_HUMAN:347:363_5hod_D_1 ModCRE Homology model AAAATTTTTAAAAATTTT Region 347-363 · 1 3D model Open · Scan
DIMER_sp_O60393_NOBOX_HUMAN:350:361_1fjl_A_1 ModCRE Homology model CTAAGTTAATTAA Region 350-361 · 1 3D model Open · Scan
DIMER_sp_O60393_NOBOX_HUMAN:350:361_1hdd_D_1 ModCRE Homology model GGCAAAAATTTAAAA Region 350-361 · 1 3D model Open · Scan
DIMER_sp_O60393_NOBOX_HUMAN:350:361_3hdd_A_1 ModCRE Homology model GGGAAAAATTTTTAAT Region 350-361 · 1 3D model Open · Scan
DIMER_sp_O60393_NOBOX_HUMAN:350:361_4qtr_B_1 ModCRE Homology model GTAAATTTAGTTTA Region 350-361 · 1 3D model Open · Scan
TFS_sp_O60393_NOBOX_HUMAN:350:361_3a01_B_1 ModCRE Homology model GGTAAAAATTATAAAG Region 350-361 · 1 3D model Open · Scan
TFS_sp_O60393_NOBOX_HUMAN:350:363_3lnq_A_1 ModCRE Homology model GCAAAAAATTTAAA Region 350-363 · 1 3D model Open · Scan
TFS_sp_O60393_NOBOX_HUMAN:350:364_2lkx_A_1 ModCRE Homology model AAAAAAATTTTTA Region 350-364 · 1 3D model Open · Scan
TFS_sp_O60393_NOBOX_HUMAN:350:366_2me6_A_1 ModCRE Homology model TATAAAATTTTTGT Region 350-366 · 1 3D model Open · Scan
TFS_sp_O60393_NOBOX_HUMAN:350:368_1ahd_P_1 ModCRE Homology model TTGAGTAATTTGCG Region 350-368 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 691 aa
272-318
347-368

Region 272-318 0 PWM

Residues
47 aa
Domains
PF00046 · Homeodomain
3D models
10 active PDBs · 10 summary rows
Templates
1FJL, 1HDD, 2LKX, 3A01, 3CMY, 3HDD, 3LNQ, 4J19
Sources
Predicted = Low
Scan this region Show models

Region 347-368 10 PWM

Residues
22 aa
Domains
No overlapping PFAM annotation recorded
3D models
10 active PDBs
Templates
1AHD, 1FJL, 1HDD, 2LKX, 2ME6, 3A01, 3HDD, 3LNQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
20 active PDB models 10 summary rows
Region 272-31810 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:272:315_4j19_B_1 4j19 272-315 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:272:318_1fjl_A_1 1fjl 272-318 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:273:318_3a01_B_1 3a01 273-318 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:274:318_1hdd_D_1 1hdd 274-318 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:274:318_3hdd_B_1 3hdd 274-318 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:272:318_1fjl_A_1 1fjl 272-318 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:272:318_2lkx_A_1 2lkx 272-318 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:272:318_3cmy_A_1 3cmy 272-318 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:273:318_3a01_B_1 3a01 273-318 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:276:318_3lnq_A_1 3lnq 276-318 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 3lnq 272:318 276 318 P:A · DNA:B,C 53.5% / 62.8% 74 View · PDB TFS_sp_O60393_NOBOX_HUMAN:276:318_3lnq_A_1
1 3a01 272:318 272,273 316,318 P:A,B · DNA:C,D 50.0% / 63.0% 57,80 View · PDB DIMER_sp_O60393_NOBOX_HUMAN:273:318_3a01_B_1
2 3a01 272:318 272,273 316,318 P:A,B · DNA:C,D 50.0% / 63.0% 57,80 View · PDB TFS_sp_O60393_NOBOX_HUMAN:273:318_3a01_B_1
3 3cmy 272:318 272 318 P:A · DNA:B,C 42.6% / 68.1% 78 View · PDB TFS_sp_O60393_NOBOX_HUMAN:272:318_3cmy_A_1
4 2lkx 272:318 272 318 P:A · DNA:B,C 42.6% / 59.6% 69 View · PDB TFS_sp_O60393_NOBOX_HUMAN:272:318_2lkx_A_1
2 1fjl 272:318 272,272 318,318 P:A,B · DNA:D,E 40.4% / 63.8% 72,82 View · PDB DIMER_sp_O60393_NOBOX_HUMAN:272:318_1fjl_A_1
5 1fjl 272:318 272,272 318,318 P:A,B · DNA:D,E 40.4% / 63.8% 72,82 View · PDB TFS_sp_O60393_NOBOX_HUMAN:272:318_1fjl_A_1
3 4j19 272:318 275,272 315,315 P:A,B · DNA:C,D 36.4% / 52.3% 53,57 View · PDB DIMER_sp_O60393_NOBOX_HUMAN:272:315_4j19_B_1
4 3hdd 272:318 276,274 318,318 P:A,B · DNA:C,D 26.7% / 60.0% 78,80 View · PDB DIMER_sp_O60393_NOBOX_HUMAN:274:318_3hdd_B_1
5 1hdd 272:318 274,274 318,318 P:C,D · DNA:A,B 26.7% / 60.0% 78,78 View · PDB DIMER_sp_O60393_NOBOX_HUMAN:274:318_1hdd_D_1
Region 347-36810 models
Actions
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:347:363_5hod_D_1 5hod 347-363 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:350:361_1fjl_A_1 1fjl 350-361 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:350:361_1hdd_D_1 1hdd 350-361 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:350:361_3hdd_A_1 3hdd 350-361 View model · PDB
Predicted = Low DIMER_sp_O60393_NOBOX_HUMAN:350:361_4qtr_B_1 4qtr 350-361 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:350:361_3a01_B_1 3a01 350-361 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:350:363_3lnq_A_1 3lnq 350-363 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:350:364_2lkx_A_1 2lkx 350-364 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:350:366_2me6_A_1 2me6 350-366 View model · PDB
Predicted = Low TFS_sp_O60393_NOBOX_HUMAN:350:368_1ahd_P_1 1ahd 350-368 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
273-317PF00046Homeodomainoverlaps 272-318