ModCRE DB

Transcription factor

O75030 - MITF

Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 526 aa

6 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known6
MotifPredictionSourceDNA bindingSupportLogoActions
MA0620.2 Known JASPAR TAAGGTCACGTGACCTTA Direct PWM Open · Scan
MA0620.3 Known JASPAR TAAAGTCACGTGACTTTA Direct PWM Open · Scan
MA0620.4 Known JASPAR GTCACGTGAC Direct PWM Open · Scan
M08058_2.00 Known CisBP TAAGGTCACGTGACCTTA Direct PWM Open · Scan
M08740_2.00 Known CisBP TCACGTGACC Direct PWM Open · Scan
MITF_HUMAN.H11MO.0.A Known HOCOMOCO TCACGTGACC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 526 aa
308-363

Region 308-363 0 PWM

Residues
56 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
4H10
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 308-3631 model
Actions
Predicted = Low DIMER_O75030:308:363_4h10_B_1 4h10 308-363 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
56-194PF15951MITF/TFEB/TFEC/TFE3 N-terminusNo overlap with loaded model regions
312-365PF00010Helix-loop-helix DNA-binding domainoverlaps 308-363
397-521PF11851Domain of unknown function (DUF3371)No overlap with loaded model regions