Transcription factor

O75123 - ZNF623

Zinc finger protein 623

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 536 aa

105 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)94

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M08365_2.00	NN 70-40%	CisBP	GCCAGCAGCCATCAG	66.1% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	65.4% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	64.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	63.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	63.0% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	62.3% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	62.3% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	61.9% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	61.9% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	61.9% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	61.9% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	61.8% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.5% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	61.1% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	60.7% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	60.7% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	60.7% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	59.5% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	59.5% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	59.5% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	58.6% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	57.9% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	57.7% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	57.2% identity		Open · Scan
M07691_2.00	NN 70-40%	CisBP	CCTGCAGCCACCTTGGCCTTG	57.2% identity		Open · Scan
M07707_2.00	NN 70-40%	CisBP	TCCCGC	57.2% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	56.9% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	56.9% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	56.9% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	56.8% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	56.7% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	56.6% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	56.6% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	56.2% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	56.2% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	55.7% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	55.6% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	55.4% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	55.3% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	55.1% identity		Open · Scan
M08903_2.00	NN 70-40%	CisBP	ATTCCATTCTATTCCATTCT	54.9% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	54.8% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	54.7% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	54.7% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	54.7% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	54.6% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	54.6% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	54.6% identity		Open · Scan
M04610_2.00	NN 70-40%	CisBP	CGGCGACGCGAACAC	54.5% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	54.5% identity		Open · Scan
MA1600.1	NN 70-40%	JASPAR	ATACAGTCCACCCCTTTA	54.5% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	54.4% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.0% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	53.8% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	53.7% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	53.7% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	53.7% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	53.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	53.3% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	53.3% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	53.2% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	53.0% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	53.0% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	53.0% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	52.8% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	52.7% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	52.2% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	52.0% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	51.9% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	51.8% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	51.8% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	51.7% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	51.7% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	51.6% identity		Open · Scan
M04505_2.00	NN 70-40%	CisBP	AGCTTTTCCCACAC	51.3% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	51.3% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	51.2% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	51.2% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	51.1% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	51.0% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	51.0% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	51.0% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	50.9% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	50.8% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	50.7% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	50.6% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	50.5% identity		Open · Scan
M02913_2.00	NN 70-40%	CisBP	TTCGTGGCATTTTTCTA	50.3% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	50.2% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	50.2% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	50.1% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	50.0% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	50.0% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	50.0% identity		Open · Scan

ModCRE11

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_O75123_ZN623_HUMAN:233:284_1llm_D_1	ModCRE	Homology model	CACGCGCGCGGG	Region 233-284 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:148:258_5ei9_E_1	ModCRE	Homology model	CCCCCCGGCCGCGGGGCC	Region 148-258 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:181:454_5v3j_E_1	ModCRE	Homology model	CGCCTGCACGCCGGGGCCCCCCTGGG	Region 181-454 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:181:454_5v3m_C_1	ModCRE	Homology model	CCGCGCCGTGGGGGGGGGGGGGGGCG	Region 181-454 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:194:341_2i13_A_1	ModCRE	Homology model	ATTAACAGGTAATTAAGGTGA	Region 194-341 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:204:482_5wjq_D_1	ModCRE	Homology model	GGGGGCGGCGGGGGGAGCGGGCGGGGGG	Region 204-482 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:79:145_5egb_A_1	ModCRE	Homology model	ACCACGGGCGGCCGGGTTA	Region 79-145 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:79:145_5ei9_E_1	ModCRE	Homology model	CCACCGGGGGCCTGGTG	Region 79-145 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:85:147_5v3j_E_1	ModCRE	Homology model	TGGGTACGGGTAAGG	Region 85-147 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:85:147_5v3m_C_1	ModCRE	Homology model	AACTGTGGGTAAAA	Region 85-147 · 1 3D model		Open · Scan
TFS_sp_O75123_ZN623_HUMAN:85:147_5wjq_D_1	ModCRE	Homology model	TTGTACGGGTTAAA	Region 85-147 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 536 aa

79-482

Region 79-482 11 PWM

Residues

404 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

12 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EGB, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

12 active PDB models 6 summary rows

Region 79-48212 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_O75123_ZN623_HUMAN:233:284_1llm_D_1	1llm	233-284	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:125:421_7w1m_H_1	7w1m	125-421	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:148:258_5ei9_E_1	5ei9	148-258	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:181:454_5v3j_E_1	5v3j	181-454	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:181:454_5v3m_C_1	5v3m	181-454	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:194:341_2i13_A_1	2i13	194-341	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:204:482_5wjq_D_1	5wjq	204-482	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:79:145_5egb_A_1	5egb	79-145	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:79:145_5ei9_E_1	5ei9	79-145	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:85:147_5v3j_E_1	5v3j	85-147	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:85:147_5v3m_C_1	5v3m	85-147	View model · PDB
Predicted = Low	TFS_sp_O75123_ZN623_HUMAN:85:147_5wjq_D_1	5wjq	85-147	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	122:482	194	341	P:A · DNA:C,D	55.4% / 67.6%	96	View · PDB TFS_sp_O75123_ZN623_HUMAN:194:341_2i13_A_1
1	5wjq	122:482	204	482	P:D · DNA:A,B	55.2% / 72.4%	99	View · PDB TFS_sp_O75123_ZN623_HUMAN:204:482_5wjq_D_1
2	5v3m	122:482	181	454	P:C · DNA:A,B	53.6% / 71.2%	98	View · PDB TFS_sp_O75123_ZN623_HUMAN:181:454_5v3m_C_1
3	5v3j	122:482	181	454	P:E · DNA:A,B	53.6% / 71.2%	98	View · PDB TFS_sp_O75123_ZN623_HUMAN:181:454_5v3j_E_1
1	1llm	122:482	233,233	284,284	P:C,D · DNA:A,B	46.2% / 63.5%	59,61	View · PDB DIMER_sp_O75123_ZN623_HUMAN:233:284_1llm_D_1
5	7w1m	122:482	125	421	P:H · DNA:F,G	36.6% / 49.7%	92	View · PDB TFS_sp_O75123_ZN623_HUMAN:125:421_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
125-145	PF00096	Zinc finger, C2H2 type	overlaps 79-482
151-173	PF00096	Zinc finger, C2H2 type	overlaps 79-482
179-201	PF00096	Zinc finger, C2H2 type	overlaps 79-482
207-229	PF00096	Zinc finger, C2H2 type	overlaps 79-482
235-257	PF00096	Zinc finger, C2H2 type	overlaps 79-482
263-285	PF00096	Zinc finger, C2H2 type	overlaps 79-482
291-313	PF00096	Zinc finger, C2H2 type	overlaps 79-482
319-341	PF00096	Zinc finger, C2H2 type	overlaps 79-482
347-369	PF00096	Zinc finger, C2H2 type	overlaps 79-482
375-397	PF00096	Zinc finger, C2H2 type	overlaps 79-482
403-425	PF00096	Zinc finger, C2H2 type	overlaps 79-482
431-453	PF00096	Zinc finger, C2H2 type	overlaps 79-482
459-481	PF00096	Zinc finger, C2H2 type	overlaps 79-482