ModCRE DB

Transcription factor

O94900 - TOX

Thymocyte selection-associated high mobility group box protein TOX (Thymus high mobility group box protein TOX)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 526 aa

4 Generated PWM 4 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE4
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_O94900_TOX_HUMAN:245:330_2gzk_A_1 ModCRE Homology model TGGGTTAAAACAAAGG Region 245-330 · 1 3D model Open · Scan
TFS_sp_O94900_TOX_HUMAN:245:332_1j5n_A_1 ModCRE Homology model AAGTTTTTTTTTCAC Region 245-332 · 1 3D model Open · Scan
TFS_sp_O94900_TOX_HUMAN:252:323_6cij_N_1 ModCRE Homology model GCCCGCTAAAGCTATAT Region 252-323 · 1 3D model Open · Scan
TFS_sp_O94900_TOX_HUMAN:259:331_3nm9_P_1 ModCRE Homology model TCGAGCCGGCGCTC Region 259-331 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 526 aa
245-332

Region 245-332 4 PWM

Residues
88 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
4 active PDBs · 4 summary rows
Templates
1J5N, 2GZK, 3NM9, 6CIJ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
4 active PDB models 4 summary rows
Region 245-3324 models · 4 summary rows
Actions
Predicted = Low TFS_sp_O94900_TOX_HUMAN:245:330_2gzk_A_1 2gzk 245-330 View model · PDB
Predicted = Low TFS_sp_O94900_TOX_HUMAN:245:332_1j5n_A_1 1j5n 245-332 View model · PDB
Predicted = Low TFS_sp_O94900_TOX_HUMAN:252:323_6cij_N_1 6cij 252-323 View model · PDB
Predicted = Low TFS_sp_O94900_TOX_HUMAN:259:331_3nm9_P_1 3nm9 259-331 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 2gzk 245:332 245 330 P:A · DNA:B,C 43.0% / 62.8% 54 View · PDB TFS_sp_O94900_TOX_HUMAN:245:330_2gzk_A_1
3 6cij 245:332 252 323 P:N · DNA:G,M 41.7% / 62.5% 52 View · PDB TFS_sp_O94900_TOX_HUMAN:252:323_6cij_N_1
1 1j5n 245:332 245 332 P:A · DNA:B,C 38.6% / 60.2% 94 View · PDB TFS_sp_O94900_TOX_HUMAN:245:332_1j5n_A_1
4 3nm9 245:332 259 331 P:P · DNA:E,F,H,I,K,L 28.8% / 56.2% 97 View · PDB TFS_sp_O94900_TOX_HUMAN:259:331_3nm9_P_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
261-329PF00505HMG (high mobility group) boxoverlaps 245-332