ModCRE DB

Transcription factor

O95409 - ZIC2

Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 532 aa

29 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M10107_2.00 Known CisBP GACCACCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)2
MotifPredictionSourceDNA bindingSupportLogoActions
M08233_2.00 NN 70+% CisBP CCCCTGCTGGG 99.0% identity Open · Scan
MA1628.1 NN 70+% JASPAR CACAGCAGGGG 97.9% identity Open · Scan
Nearest Neighbor (70% - 40%)26
MotifPredictionSourceDNA bindingSupportLogoActions
M06112_2.00 NN 70-40% CisBP CTACTTTCACCGGGG 69.2% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 68.4% identity Open · Scan
M00621_2.00 NN 70-40% CisBP CCCGCTGTGA 67.8% identity Open · Scan
MA0751.1 NN 70-40% JASPAR GACCCCCCGCTGTGC 67.1% identity Open · Scan
M09013_2.00 NN 70-40% CisBP GGCCCCCTGCTGTGA 65.3% identity Open · Scan
MA0697.1 NN 70-40% JASPAR GACCCCCCGCTGCGC 65.2% identity Open · Scan
MA0696.1 NN 70-40% JASPAR GACCCCCCGCTGTG 63.6% identity Open · Scan
M00780_2.00 NN 70-40% CisBP GACCCCCCGG 61.9% identity Open · Scan
M02673_2.00 NN 70-40% CisBP GAACCCCCA 61.2% identity Open · Scan
MA1584.1 NN 70-40% JASPAR CGACCCCCCGCTGTGC 59.7% identity Open · Scan
M03702_2.00 NN 70-40% CisBP GACCCCCCACGACGC 59.2% identity Open · Scan
M04486_2.00 NN 70-40% CisBP GACCCCCTGCTGTGC 58.8% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 58.6% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 56.7% identity Open · Scan
M01022_2.00 NN 70-40% CisBP GGACCACCCAC 53.9% identity Open · Scan
MA1491.1 NN 70-40% JASPAR AGACCACCCACGTCG 53.7% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 52.7% identity Open · Scan
M00645_2.00 NN 70-40% CisBP CGCCCACGCA 51.8% identity Open · Scan
M01024_2.00 NN 70-40% CisBP GGACCACCCA 51.5% identity Open · Scan
MA0734.1 NN 70-40% JASPAR GCGACCACACTG 51.5% identity Open · Scan
MA0753.1 NN 70-40% JASPAR CCCCCCCCAC 50.9% identity Open · Scan
MA0732.1 NN 70-40% JASPAR CTACGCCCACGCACT 50.6% identity Open · Scan
M01470_2.00 NN 70-40% CisBP CCCCCCGC 50.0% identity Open · Scan
M04409_2.00 NN 70-40% CisBP GGCGGCCATTTTGG 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M08528_2.00 NN 70-40% CisBP ACCCCACTTTTTTG 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 532 aa
273-413

Region 273-413 0 PWM

Residues
141 aa
Domains
PF18366 · Zic proteins zinc finger domain PF23561 · C2H2 zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
2GLI
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 273-4131 model
Actions
Predicted = Low TFS_O95409:273:413_2gli_A_1 2gli 273-413 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
250-295PF18366Zic proteins zinc finger domainoverlaps 273-413
302-331PF23561C2H2 zinc fingeroverlaps 273-413
333-357PF00096Zinc finger, C2H2 typeoverlaps 273-413
363-387PF00096Zinc finger, C2H2 typeoverlaps 273-413
393-415PF00096Zinc finger, C2H2 typeoverlaps 273-413