ModCRE DB

Transcription factor

O95475 - SIX6

Homeobox protein SIX6 (Homeodomain protein OPTX2) (Optic homeobox 2) (Sine oculis homeobox homolog 6)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 246 aa

5 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known5
MotifPredictionSourceDNA bindingSupportLogoActions
M05357_2.00 Known CisBP AATGATACGC Direct PWM Open · Scan
M00325_2.00 Known CisBP AATGATAC Direct PWM Open · Scan
M00326_2.00 Known CisBP ATGATAC Direct PWM Open · Scan
M00327_2.00 Known CisBP ATGATACCC Direct PWM Open · Scan
M05358_2.00 Known CisBP GCGTATCACG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 246 aa
127-182

Region 127-182 0 PWM

Residues
56 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
5ZJR
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 127-1821 model
Actions
Predicted = Low DIMER_O95475:127:182_5zjr_B_1 5zjr 127-182 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
9-123PF16878Transcriptional regulator, SIX1, N-terminal SD domainNo overlap with loaded model regions
133-184PF00046Homeodomainoverlaps 127-182