ModCRE DB

Transcription factor

O96004 - HAND1

Heart- and neural crest derivatives-expressed protein 1 (Class A basic helix-loop-helix protein 27) (bHLHa27) (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 215 aa

18 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
MA2123.1 Known JASPAR TCCAGACCT Direct PWM Open · Scan
Nearest Neighbor (>70%)1
MotifPredictionSourceDNA bindingSupportLogoActions
MA0092.1 NN 70+% JASPAR GGTCTGGCAT 92.1% identity Open · Scan
Nearest Neighbor (70% - 40%)16
MotifPredictionSourceDNA bindingSupportLogoActions
M00756_2.00 NN 70-40% CisBP CGCAGCTGTG 59.1% identity Open · Scan
MA0048.1 NN 70-40% JASPAR GCGCAGCTGCGT 59.1% identity Open · Scan
MA1529.1 NN 70-40% JASPAR GGGCCGCAGCTGCGTCCC 59.1% identity Open · Scan
MA0607.1 NN 70-40% JASPAR CCATATGT 57.7% identity Open · Scan
MA1472.1 NN 70-40% JASPAR AACAGCTGTT 57.7% identity Open · Scan
M01718_2.00 NN 70-40% CisBP AACATATGGT 57.6% identity Open · Scan
MA0633.1 NN 70-40% JASPAR ACCATATGTT 57.6% identity Open · Scan
MA1123.1 NN 70-40% JASPAR ATTCCAGATGTTT 57.6% identity Open · Scan
M03606_2.00 NN 70-40% CisBP CCACACGACGCA 54.0% identity Open · Scan
MA0832.1 NN 70-40% JASPAR GCAACAGCTGTTGT 53.8% identity Open · Scan
MA1568.1 NN 70-40% JASPAR CACCATATGGCG 53.8% identity Open · Scan
MA0665.1 NN 70-40% JASPAR AACAGCTGTT 51.9% identity Open · Scan
MA1638.1 NN 70-40% JASPAR ACCAGATGGC 51.6% identity Open · Scan
M06000_2.00 NN 70-40% CisBP CCAGATGGCACGGACACAACA 51.0% identity Open · Scan
M04156_2.00 NN 70-40% CisBP AACAGCTGACGC 50.0% identity Open · Scan
MA1618.1 NN 70-40% JASPAR AAACAGATGTTTA 50.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 215 aa
103-143

Region 103-143 0 PWM

Residues
41 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
5I50
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 103-1431 model
Actions
Predicted = Low DIMER_O96004:103:143_5i50_B_1 5i50 103-143 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
97-146PF00010Helix-loop-helix DNA-binding domainoverlaps 103-143