ModCRE DB

Transcription factor

P03372 - ESR1

Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 595 aa

16 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known16
MotifPredictionSourceDNA bindingSupportLogoActions
MA0112.1 Known JASPAR CCAGGTCACCGTGACCCC Direct PWM Open · Scan
MA0112.2 Known JASPAR GGCCCAGGTCACCCTGACCT Direct PWM Open · Scan
MA0112.3 Known JASPAR AAGGTCACGGTGACCTG Direct PWM Open · Scan
MA0112.4 Known JASPAR AGGTCACGGTGACCT Direct PWM Open · Scan
M03356_2.00 Known CisBP AAGGTCACGGTGACCTG Direct PWM Open · Scan
M05569_2.00 Known CisBP AAGGTCACGGTGACCTT Direct PWM Open · Scan
M05570_2.00 Known CisBP GAGGTCACCGCGACCTT Direct PWM Open · Scan
M05571_2.00 Known CisBP AAGGTCACCGTGACCTT Direct PWM Open · Scan
M05572_2.00 Known CisBP GAGGTCACCGTGACCTT Direct PWM Open · Scan
M07985_2.00 Known CisBP GGCCCAAGGTCACA Direct PWM Open · Scan
M08217_2.00 Known CisBP TCCAGGTCACCCTGACCT Direct PWM Open · Scan
M08218_2.00 Known CisBP CCAAGGTCAC Direct PWM Open · Scan
M09267_2.00 Known CisBP AGGTCACCCTGACCT Direct PWM Open · Scan
M09604_2.00 Known CisBP AAGGTCACCGTGACC Direct PWM Open · Scan
M11102_2.00 Known CisBP TCAGGTCACAGTGACCTGA Direct PWM Open · Scan
ESR1_HUMAN.H11MO.0.A Known HOCOMOCO AGGTCACCCTGACCT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 595 aa
180-250

Region 180-250 0 PWM

Residues
71 aa
Domains
PF02159 · Oestrogen receptor PF00105 · Double treble clef zinc finger, C4 type
3D models
1 active PDB
Templates
4OLN
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 180-2501 model
Actions
Predicted = Low DIMER_P03372:180:250_4oln_A_1 4oln 180-250 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
42-181PF02159Oestrogen receptoroverlaps 180-250
184-252PF00105Double treble clef zinc finger, C4 typeoverlaps 180-250
337-530PF00104Ligand-binding domain of nuclear hormone receptorNo overlap with loaded model regions
552-595PF12743Oestrogen-type nuclear receptor final C-terminalNo overlap with loaded model regions