ModCRE DB

Transcription factor

P0DV77 - TPRX2

Tetrapeptide repeat homeobox protein 2

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 301 aa

23 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M03250_2.00 NN 70-40% CisBP TTAATCCG 53.4% identity Open · Scan
MA0711.1 NN 70-40% JASPAR TTAATCCG 53.4% identity Open · Scan
M00679_2.00 NN 70-40% CisBP TTAATCCC 50.8% identity Open · Scan
M03076_2.00 NN 70-40% CisBP TTAATTAAATTAA 50.8% identity Open · Scan
MA0874.1 NN 70-40% JASPAR GTCCATTAATTAATGGA 50.8% identity Open · Scan
M09208_2.00 NN 70-40% CisBP CCTAATCCTCTTA 50.0% identity Open · Scan
M09569_2.00 NN 70-40% CisBP GTTAATCCCT 50.0% identity Open · Scan
MA0467.1 NN 70-40% JASPAR AAGAGGATTAG 50.0% identity Open · Scan
ModCRE15
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_P0DV77_TPRX2_HUMAN:18:77_1puf_A_1 ModCRE Homology model TTTTTAATTAATTATATGG Region 18-77 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:19:78_1fjl_A_1 ModCRE Homology model TTAATTAAATTAG Region 19-78 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:21:74_3a01_B_1 ModCRE Homology model AATTTAATTAATGACTT Region 21-74 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:24:77_4qtr_A_1 ModCRE Homology model GCAAATTTATTGC Region 24-77 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_1b8i_A_1 ModCRE Homology model GGTAATTAATCAA Region 24-78 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_4cyc_A_1 ModCRE Homology model GCCAATTAATCTT Region 24-78 · 1 3D model Open · Scan
DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_4uus_A_1 ModCRE Homology model GGTAATTTATTTG Region 24-78 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:16:77_2me6_A_1 ModCRE Homology model GATTTAATTTTTTT Region 16-77 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:20:74_2lkx_A_1 ModCRE Homology model GGGGAATAATTGA Region 20-74 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:20:75_1fjl_B_1 ModCRE Homology model CGGCCCTAATTAA Region 20-75 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:20:78_3cmy_A_1 ModCRE Homology model TATTTTA Region 20-78 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:20:85_1ahd_P_1 ModCRE Homology model ATTAAATGGTTTAT Region 20-85 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:24:77_4qtr_A_1 ModCRE Homology model TCAAATTGATTGC Region 24-77 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:24:78_1b8i_A_1 ModCRE Homology model ACCAATTTTTTTC Region 24-78 · 1 3D model Open · Scan
TFS_sp_P0DV77_TPRX2_HUMAN:24:84_7q4n_K_1 ModCRE Homology model CCAGGAATATTTTCGGT Region 24-84 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 301 aa
9-85

Region 9-85 15 PWM

Residues
77 aa
Domains
PF00046 · Homeodomain
3D models
16 active PDBs · 10 summary rows
Templates
1AHD, 1B8I, 1FJL, 1PUF, 2LKX, 2ME6, 3A01, 3CMY, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 10 summary rows
Region 9-8516 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:18:77_1puf_A_1 1puf 18-77 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:19:78_1fjl_A_1 1fjl 19-78 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:21:74_3a01_B_1 3a01 21-74 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:24:77_4qtr_A_1 4qtr 24-77 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_1b8i_A_1 1b8i 24-78 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_4cyc_A_1 4cyc 24-78 View model · PDB
Predicted = Low DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_4uus_A_1 4uus 24-78 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:16:77_2me6_A_1 2me6 16-77 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:19:78_1fjl_A_1 1fjl 19-78 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:20:74_2lkx_A_1 2lkx 20-74 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:20:75_1fjl_B_1 1fjl 20-75 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:20:78_3cmy_A_1 3cmy 20-78 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:20:85_1ahd_P_1 1ahd 20-85 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:24:77_4qtr_A_1 4qtr 24-77 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:24:78_1b8i_A_1 1b8i 24-78 View model · PDB
Predicted = Low TFS_sp_P0DV77_TPRX2_HUMAN:24:84_7q4n_K_1 7q4n 24-84 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 2lkx 16:93 20 74 P:A · DNA:B,C 45.5% / 69.1% 80 View · PDB TFS_sp_P0DV77_TPRX2_HUMAN:20:74_2lkx_A_1
5 3a01 16:93 9,21 78,74 P:A,B · DNA:C,D 44.4% / 61.1% 89,94 View · PDB DIMER_sp_P0DV77_TPRX2_HUMAN:21:74_3a01_B_1
1 1fjl 16:93 19,20 78,75 P:A,B · DNA:D,E 43.3% / 68.3% 92,98 View · PDB TFS_sp_P0DV77_TPRX2_HUMAN:19:78_1fjl_A_1
1 1fjl 16:93 19,20 78,75 P:A,B · DNA:D,E 43.3% / 68.3% 92,98 View · PDB DIMER_sp_P0DV77_TPRX2_HUMAN:19:78_1fjl_A_1
3 4uus 16:93 24,44 78,74 P:A,B · DNA:C,D 41.8% / 60.0% 82,44 View · PIR DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_4uus_A_1
4 1b8i 16:93 24,44 78,74 P:A,B · DNA:C,D 41.8% / 60.0% 88,53 View · PIR DIMER_sp_P0DV77_TPRX2_HUMAN:24:78_1b8i_A_1
4 7q4n 16:93 24 84 P:K · DNA:A,D 41.3% / 63.5% 92 View · PDB TFS_sp_P0DV77_TPRX2_HUMAN:24:84_7q4n_K_1
5 3cmy 16:93 20 78 P:A · DNA:B,C 40.7% / 61.0% 98 View · PDB TFS_sp_P0DV77_TPRX2_HUMAN:20:78_3cmy_A_1
2 1puf 16:93 18,21 77,74 P:A,B · DNA:D,E 38.3% / 63.3% 77,73 View · PDB DIMER_sp_P0DV77_TPRX2_HUMAN:18:77_1puf_A_1
3 1ahd 16:93 20 85 P:P · DNA:A,B 34.8% / 60.6% 97 View · PDB TFS_sp_P0DV77_TPRX2_HUMAN:20:85_1ahd_P_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
21-74PF00046Homeodomainoverlaps 9-85