ModCRE DB

Transcription factor

P10071 - GLI3

Transcription activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcription repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)]

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1580 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
MA1491.1 Known JASPAR AGACCACCCACGTCG Direct PWM Open · Scan
MA1491.2 Known JASPAR GGACCACCCACGTCGC Direct PWM Open · Scan
MA1491.3 Known JASPAR GGACCACCCACGTCG Direct PWM Open · Scan
M02642_2.00 Known CisBP GACCACCCACG Direct PWM Open · Scan
M04416_2.00 Known CisBP AGACCACCCACGTCG Direct PWM Open · Scan
M04417_2.00 Known CisBP CTACGTGGGTGGTCT Direct PWM Open · Scan
M08875_2.00 Known CisBP GGACCACCCAA Direct PWM Open · Scan
GLI3_HUMAN.H11MO.0.B Known HOCOMOCO CTGGGTGGTCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1580 aa
479-633

Region 479-633 0 PWM

Residues
155 aa
Domains
PF23561 · C2H2 zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
2GLI
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 479-6331 model
Actions
Predicted = Low TFS_P10071:479:633_2gli_A_1 2gli 479-633 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
515-544PF23561C2H2 zinc fingeroverlaps 479-633
546-570PF00096Zinc finger, C2H2 typeoverlaps 479-633
607-632PF00096Zinc finger, C2H2 typeoverlaps 479-633