ModCRE DB

Transcription factor

P12524 - MYCL

Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 364 aa

10 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M04113_2.00 NN 70-40% CisBP GCACATGGTAAGCACATGG 52.0% identity Open · Scan
MA0058.1 NN 70-40% JASPAR AACCACGTGA 52.0% identity Open · Scan
M08778_2.00 NN 70-40% CisBP GAGCACGTGGC 50.9% identity Open · Scan
ModCRE7
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_P12524_MYCL_HUMAN:279:331_1hlo_B_1 ModCRE Homology model ACCCACGTGGT Region 279-331 · 1 3D model Open · Scan
DIMER_sp_P12524_MYCL_HUMAN:282:363_1nkp_A_1 ModCRE Homology model AGGGCCCACGGGGGGCCT Region 282-363 · 1 3D model Open · Scan
TFS_sp_P12524_MYCL_HUMAN:279:331_1hlo_A_1 ModCRE Homology model ACCACGTGGGG Region 279-331 · 1 3D model Open · Scan
TFS_sp_P12524_MYCL_HUMAN:279:331_1hlo_B_1 ModCRE Homology model ACCCCATGTGG Region 279-331 · 1 3D model Open · Scan
TFS_sp_P12524_MYCL_HUMAN:282:331_1nlw_B_1 ModCRE Homology model ACGCAGCACGTGTGCCAT Region 282-331 · 1 3D model Open · Scan
TFS_sp_P12524_MYCL_HUMAN:282:363_1nkp_A_1 ModCRE Homology model AGGCCCCACGTGGGGCCT Region 282-363 · 1 3D model Open · Scan
TFS_sp_P12524_MYCL_HUMAN:282:363_1nkp_B_1 ModCRE Homology model CGGGCGCGCGTGGGGCCC Region 282-363 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 364 aa
277-363

Region 277-363 7 PWM

Residues
87 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
16 active PDBs · 10 summary rows
Templates
1AM9, 1HLO, 1NKP, 1NLW, 5GNJ, 5I50, 8OTS, 8OTT
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 10 summary rows
Region 277-36316 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:277:361_5i50_B_1 5i50 277-361 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:279:331_1hlo_A_1 1hlo 279-331 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:279:331_1hlo_B_1 1hlo 279-331 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:282:330_8ott_M_1 8ott 282-330 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:282:348_1am9_B_1 1am9 282-348 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:282:348_1am9_D_1 1am9 282-348 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:282:363_1nkp_A_1 1nkp 282-363 View model · PDB
Predicted = Low DIMER_sp_P12524_MYCL_HUMAN:285:359_5gnj_G_1 5gnj 285-359 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:277:361_5i50_B_1 5i50 277-361 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:279:331_1hlo_A_1 1hlo 279-331 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:279:331_1hlo_B_1 1hlo 279-331 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:282:330_8ott_M_1 8ott 282-330 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:282:331_1nlw_B_1 1nlw 282-331 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:282:358_8ots_M_1 8ots 282-358 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:282:363_1nkp_A_1 1nkp 282-363 View model · PDB
Predicted = Low TFS_sp_P12524_MYCL_HUMAN:282:363_1nkp_B_1 1nkp 282-363 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
3 8ott 274:363 282,282 330,331 P:M,N · DNA:I,J 61.2% / 75.5% 92,96 View · PDB DIMER_sp_P12524_MYCL_HUMAN:282:330_8ott_M_1
4 8ott 274:363 282,282 330,331 P:M,N · DNA:I,J 61.2% / 75.5% 92,96 View · PDB TFS_sp_P12524_MYCL_HUMAN:282:330_8ott_M_1
4 1hlo 274:363 279,279 331,331 P:A,B · DNA:C,D 50.9% / 66.0% 65,71 View · PDB DIMER_sp_P12524_MYCL_HUMAN:279:331_1hlo_A_1
5 1hlo 274:363 279,279 331,331 P:A,B · DNA:C,D 50.9% / 66.0% 65,71 View · PDB TFS_sp_P12524_MYCL_HUMAN:279:331_1hlo_A_1
2 8ots 274:363 282 358 P:M · DNA:I,J 48.1% / 72.7% 97 View · PDB TFS_sp_P12524_MYCL_HUMAN:282:358_8ots_M_1
1 1nkp 274:363 282,282 363,363 P:A,B · DNA:F,G 47.6% / 70.7% 93,97 View · PDB DIMER_sp_P12524_MYCL_HUMAN:282:363_1nkp_A_1
1 1nkp 274:363 282,282 363,363 P:A,B · DNA:F,G 47.6% / 70.7% 93,97 View · PDB TFS_sp_P12524_MYCL_HUMAN:282:363_1nkp_B_1
2 5i50 274:363 277,277 361,361 P:A,B · DNA:C,D 44.7% / 67.1% 92,88 View · PIR DIMER_sp_P12524_MYCL_HUMAN:277:361_5i50_B_1
3 5i50 274:363 277,277 361,361 P:A,B · DNA:C,D 44.7% / 67.1% 92,88 View · PDB TFS_sp_P12524_MYCL_HUMAN:277:361_5i50_B_1
5 5gnj 274:363 285,285 359,359 P:G,I · DNA:K,L 33.3% / 53.3% 98,96 View · PDB DIMER_sp_P12524_MYCL_HUMAN:285:359_5gnj_G_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-43PF01056Myc amino-terminal regionNo overlap with loaded model regions
86-131PF01056Myc amino-terminal regionNo overlap with loaded model regions
160-221PF01056Myc amino-terminal regionNo overlap with loaded model regions
282-333PF00010Helix-loop-helix DNA-binding domainoverlaps 277-363