Transcription factor

P17021 - ZNF17

Zinc finger protein 17 (Zinc finger protein HPF3) (Zinc finger protein KOX10)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 662 aa

75 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07681_2.00	Known	CisBP	GATCTTCAGGTGCCTGCTCAGGCGAGCGCC	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)68

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	62.5% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	62.3% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	62.3% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	61.4% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	61.1% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	61.1% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	60.2% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	60.2% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.2% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	60.0% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	60.0% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	59.0% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	58.8% identity		Open · Scan
M07680_2.00	NN 70-40%	CisBP	AACCCCAAC	58.7% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	58.5% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	57.4% identity		Open · Scan
M07691_2.00	NN 70-40%	CisBP	CCTGCAGCCACCTTGGCCTTG	57.2% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	56.6% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	56.4% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	56.4% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	56.1% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	55.7% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	55.6% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	55.5% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	55.3% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	55.3% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	55.2% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	54.4% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.4% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	54.4% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	54.3% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	54.0% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	53.9% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	53.6% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	53.6% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	53.4% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	53.2% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	53.2% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	53.1% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	53.1% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	53.0% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	52.9% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	52.8% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	52.8% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	52.8% identity		Open · Scan
M08903_2.00	NN 70-40%	CisBP	ATTCCATTCTATTCCATTCT	52.8% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	52.6% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	52.6% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	52.6% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	52.4% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	51.9% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	51.6% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	51.6% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	50.9% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	50.9% identity		Open · Scan
M07631_2.00	NN 70-40%	CisBP	AATTTCAAAAATGCTATGGGC	50.8% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	50.8% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	50.8% identity		Open · Scan
MA1580.1	NN 70-40%	JASPAR	TGTACAGTAT	50.7% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.7% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	50.6% identity		Open · Scan
M07706_2.00	NN 70-40%	CisBP	GTCTTTGAGAGGGCCCAGATGTTGGACTTA	50.6% identity		Open · Scan
M07582_2.00	NN 70-40%	CisBP	TCCCTG	50.5% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	50.5% identity		Open · Scan
M07633_2.00	NN 70-40%	CisBP	CTCTCGTTGTGCCTTTGCCAT	50.2% identity		Open · Scan
M00217_2.00	NN 70-40%	CisBP	TTACTCAATAT	50.0% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	50.0% identity		Open · Scan
M08390_2.00	NN 70-40%	CisBP	GCTTTGTTGACTCAC	50.0% identity		Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_sp_P17021_ZNF17_HUMAN:111:175_5v3j_E_1	ModCRE	Homology model	AACCCTGGACGGGGTAAA	Region 111-175 · 1 3D model		Open · Scan
TFS_sp_P17021_ZNF17_HUMAN:111:175_5v3m_C_1	ModCRE	Homology model	ATTCCCGCACGGGTGCT	Region 111-175 · 1 3D model		Open · Scan
TFS_sp_P17021_ZNF17_HUMAN:111:175_5wjq_D_1	ModCRE	Homology model	AATCTCGCGCGGGGCGG	Region 111-175 · 1 3D model		Open · Scan
TFS_sp_P17021_ZNF17_HUMAN:140:188_2kmk_A_1	ModCRE	Homology model	GCCTAAAATTTTC	Region 140-188 · 1 3D model		Open · Scan
TFS_sp_P17021_ZNF17_HUMAN:141:175_2i13_A_1	ModCRE	Homology model	CTGCTTATGTAC	Region 141-175 · 1 3D model		Open · Scan
TFS_sp_P17021_ZNF17_HUMAN:141:188_2i13_A_1	ModCRE	Homology model	TAAGGGCTCGAGA	Region 141-188 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 662 aa

111-188

199-661

Region 111-188 6 PWM

Residues

78 aa

Domains

No overlapping PFAM annotation recorded

3D models

6 active PDBs

Templates

2I13, 2KMK, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

Region 199-661 0 PWM

Residues

463 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

12 active PDB models 6 summary rows

Region 111-1886 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:111:175_5v3j_E_1	5v3j	111-175	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:111:175_5v3m_C_1	5v3m	111-175	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:111:175_5wjq_D_1	5wjq	111-175	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:140:188_2kmk_A_1	2kmk	140-188	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:141:175_2i13_A_1	2i13	141-175	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:141:188_2i13_A_1	2i13	141-188	View model · PDB

Region 199-6616 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_P17021_ZNF17_HUMAN:496:545_1llm_C_1	1llm	496-545	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:199:352_2i13_A_1	2i13	199-352	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:245:521_5v3j_E_1	5v3j	245-521	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:245:521_5v3m_C_1	5v3m	245-521	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:358:656_7w1m_H_1	7w1m	358-656	View model · PDB
Predicted = Low	TFS_sp_P17021_ZNF17_HUMAN:383:661_5wjq_D_1	5wjq	383-661	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	181:661	199	352	P:A · DNA:C,D	53.9% / 66.9%	100	View · PDB TFS_sp_P17021_ZNF17_HUMAN:199:352_2i13_A_1
1	5wjq	181:661	383	661	P:D · DNA:A,B	52.7% / 67.7%	99	View · PDB TFS_sp_P17021_ZNF17_HUMAN:383:661_5wjq_D_1
2	5v3m	181:661	245	521	P:C · DNA:A,B	52.3% / 66.8%	100	View · PDB TFS_sp_P17021_ZNF17_HUMAN:245:521_5v3m_C_1
3	5v3j	181:661	245	521	P:E · DNA:A,B	52.3% / 66.8%	100	View · PDB TFS_sp_P17021_ZNF17_HUMAN:245:521_5v3j_E_1
1	1llm	181:661	496,496	545,545	P:C,D · DNA:A,B	44.0% / 60.0%	57,58	View · PDB DIMER_sp_P17021_ZNF17_HUMAN:496:545_1llm_C_1
5	7w1m	181:661	358	656	P:H · DNA:F,G	35.4% / 51.0%	92	View · PDB TFS_sp_P17021_ZNF17_HUMAN:358:656_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
8-48	PF01352	KRAB box	No overlap with loaded model regions
190-212	PF00096	Zinc finger, C2H2 type	overlaps 199-661
218-240	PF00096	Zinc finger, C2H2 type	overlaps 199-661
246-268	PF00096	Zinc finger, C2H2 type	overlaps 199-661
274-296	PF00096	Zinc finger, C2H2 type	overlaps 199-661
302-324	PF00096	Zinc finger, C2H2 type	overlaps 199-661
332-352	PF00096	Zinc finger, C2H2 type	overlaps 199-661
358-380	PF00096	Zinc finger, C2H2 type	overlaps 199-661
386-408	PF00096	Zinc finger, C2H2 type	overlaps 199-661
414-436	PF00096	Zinc finger, C2H2 type	overlaps 199-661
442-464	PF00096	Zinc finger, C2H2 type	overlaps 199-661
470-492	PF00096	Zinc finger, C2H2 type	overlaps 199-661
498-520	PF00096	Zinc finger, C2H2 type	overlaps 199-661
526-548	PF00096	Zinc finger, C2H2 type	overlaps 199-661
554-576	PF00096	Zinc finger, C2H2 type	overlaps 199-661
582-604	PF00096	Zinc finger, C2H2 type	overlaps 199-661
610-632	PF00096	Zinc finger, C2H2 type	overlaps 199-661
638-660	PF00096	Zinc finger, C2H2 type	overlaps 199-661