ModCRE DB

Transcription factor

P17023 - ZNF19

Zinc finger protein 19 (Zinc finger protein KOX12)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 458 aa

71 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07603_2.00 Known CisBP TGCCCCGTCAGGGCCCCT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)64
MotifPredictionSourceDNA bindingSupportLogoActions
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 67.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 64.7% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 61.4% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 61.1% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 60.2% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 60.0% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.0% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 60.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 60.0% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 58.8% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 58.3% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 58.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 57.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 57.6% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 57.6% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 56.9% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 56.7% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 56.2% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 55.9% identity Open · Scan
M07666_2.00 NN 70-40% CisBP ATCTAGCCCCTGCCTACC 55.8% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 55.5% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 55.4% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 55.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 55.2% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 55.2% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 54.9% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 54.9% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 54.3% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 54.2% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 54.1% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 54.1% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 54.1% identity Open · Scan
M08263_2.00 NN 70-40% CisBP ATCTCGGCACTTTGGGAGGCCA 54.1% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 54.1% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 54.0% identity Open · Scan
M08381_2.00 NN 70-40% CisBP ACATTTTGTCCTCCTAGTCCT 53.8% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.7% identity Open · Scan
MA0528.1 NN 70-40% JASPAR GGAGGAGGAGGGGGAGGAGGA 53.6% identity Open · Scan
M07638_2.00 NN 70-40% CisBP TGCAGCTCCCTGCCC 53.4% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 53.0% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 52.7% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.7% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 52.7% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 52.5% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 52.5% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 52.2% identity Open · Scan
M07727_2.00 NN 70-40% CisBP CGCCGCCTCCCC 52.1% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 52.0% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 51.9% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 51.7% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 51.5% identity Open · Scan
M07754_2.00 NN 70-40% CisBP CGCCCCCTCCCT 51.4% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 51.4% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 51.3% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 51.2% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 51.0% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 51.0% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 51.0% identity Open · Scan
M04515_2.00 NN 70-40% CisBP TATGCTATAACAAGCAGCCCC 50.6% identity Open · Scan
M08234_2.00 NN 70-40% CisBP GTCAACTTGACTGGGCCA 50.6% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 50.5% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 50.4% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 50.2% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_P17023_ZNF19_HUMAN:299:350_1llm_D_1 ModCRE Homology model TCGCCGCGCGGA Region 299-350 · 1 3D model Open · Scan
TFS_sp_P17023_ZNF19_HUMAN:157:436_5wjq_D_1 ModCRE Homology model CCGTGCGGGAACCCCGGGGCCTTTTTTT Region 157-436 · 1 3D model Open · Scan
TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3j_E_1 ModCRE Homology model GGACCCCCCCCCCCCCCCCGATTCAA Region 160-436 · 1 3D model Open · Scan
TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3m_C_1 ModCRE Homology model CGCACCCCCCCCCCCCCCGGGTTGGA Region 160-436 · 1 3D model Open · Scan
TFS_sp_P17023_ZNF19_HUMAN:170:323_2i13_A_1 ModCRE Homology model TGAAAGAAGTAGTAGGCAAGT Region 170-323 · 1 3D model Open · Scan
TFS_sp_P17023_ZNF19_HUMAN:186:296_5ei9_E_1 ModCRE Homology model TGGGCCCCCCTCCGGGGC Region 186-296 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 458 aa
157-436

Region 157-436 6 PWM

Residues
280 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 157-4366 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P17023_ZNF19_HUMAN:299:350_1llm_D_1 1llm 299-350 View model · PDB
Predicted = Low TFS_sp_P17023_ZNF19_HUMAN:157:436_5wjq_D_1 5wjq 157-436 View model · PDB
Predicted = Low TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3j_E_1 5v3j 160-436 View model · PDB
Predicted = Low TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3m_C_1 5v3m 160-436 View model · PDB
Predicted = Low TFS_sp_P17023_ZNF19_HUMAN:170:323_2i13_A_1 2i13 170-323 View model · PDB
Predicted = Low TFS_sp_P17023_ZNF19_HUMAN:186:296_5ei9_E_1 5ei9 186-296 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 155:436 186 296 P:E · DNA:A,B 58.6% / 71.2% 100 View · PDB TFS_sp_P17023_ZNF19_HUMAN:186:296_5ei9_E_1
4 2i13 155:436 170 323 P:A · DNA:C,D 55.8% / 68.8% 100 View · PDB TFS_sp_P17023_ZNF19_HUMAN:170:323_2i13_A_1
1 5wjq 155:436 157 436 P:D · DNA:A,B 48.9% / 67.5% 99 View · PDB TFS_sp_P17023_ZNF19_HUMAN:157:436_5wjq_D_1
2 5v3m 155:436 160 436 P:C · DNA:A,B 46.6% / 66.4% 100 View · PDB TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3m_C_1
3 5v3j 155:436 160 436 P:E · DNA:A,B 46.6% / 66.4% 100 View · PDB TFS_sp_P17023_ZNF19_HUMAN:160:436_5v3j_E_1
1 1llm 155:436 299,299 350,350 P:C,D · DNA:A,B 44.2% / 67.3% 59,61 View · PDB DIMER_sp_P17023_ZNF19_HUMAN:299:350_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
13-54PF01352KRAB boxNo overlap with loaded model regions
161-183PF00096Zinc finger, C2H2 typeoverlaps 157-436
189-211PF00096Zinc finger, C2H2 typeoverlaps 157-436
217-239PF00096Zinc finger, C2H2 typeoverlaps 157-436
245-267PF00096Zinc finger, C2H2 typeoverlaps 157-436
273-295PF00096Zinc finger, C2H2 typeoverlaps 157-436
301-323PF00096Zinc finger, C2H2 typeoverlaps 157-436
329-351PF00096Zinc finger, C2H2 typeoverlaps 157-436
357-379PF00096Zinc finger, C2H2 typeoverlaps 157-436
385-407PF00096Zinc finger, C2H2 typeoverlaps 157-436