ModCRE DB

Transcription factor

P17025 - ZNF182

Zinc finger protein 182 (Zinc finger protein 21) (Zinc finger protein KOX14)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 639 aa

64 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07597_2.00 Known CisBP CCTTTTGTTTTT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)62
MotifPredictionSourceDNA bindingSupportLogoActions
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 64.2% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 63.5% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 62.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 62.3% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 62.1% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 61.1% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 61.1% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 61.1% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 60.5% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 60.1% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 60.1% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 60.0% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 59.3% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 59.2% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 59.1% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 58.8% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 58.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 58.8% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 58.7% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 58.4% identity Open · Scan
M07706_2.00 NN 70-40% CisBP GTCTTTGAGAGGGCCCAGATGTTGGACTTA 58.3% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 58.3% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 58.3% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 57.7% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 57.2% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 56.8% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 56.6% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 56.2% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 56.1% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 55.8% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 55.8% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 55.2% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 54.4% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 54.2% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 53.7% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 53.5% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 53.2% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 53.2% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 53.0% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 52.9% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 52.9% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 52.2% identity Open · Scan
M08859_2.00 NN 70-40% CisBP CATTTTTTCCTCCTAGGCCT 51.9% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 51.8% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 51.7% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 51.6% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 51.6% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 51.4% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 51.3% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 51.2% identity Open · Scan
M08903_2.00 NN 70-40% CisBP ATTCCATTCTATTCCATTCT 51.0% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 50.9% identity Open · Scan
M00774_2.00 NN 70-40% CisBP TTAGTATACACAAGT 50.6% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.6% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 50.5% identity Open · Scan
MA0528.1 NN 70-40% JASPAR GGAGGAGGAGGGGGAGGAGGA 50.3% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 50.0% identity Open · Scan
M04555_2.00 NN 70-40% CisBP GCCACGCCCCCGCCACGCCCAC 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 50.0% identity Open · Scan
MA1512.1 NN 70-40% JASPAR GCCACGCCCAC 50.0% identity Open · Scan
ModCRE1
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_P17025_ZN182_HUMAN:511:620_5ei9_E_1 ModCRE Homology model CCCCGGGGGGGGGGGCC Region 511-620 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 639 aa
232-620

Region 232-620 1 PWM

Residues
389 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 232-6207 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P17025_ZN182_HUMAN:232:276_1llm_D_1 1llm 232-276 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:261:537_5v3j_E_1 5v3j 261-537 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:261:537_5v3m_C_1 5v3m 261-537 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:287:565_5wjq_D_1 5wjq 287-565 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:318:616_7w1m_H_1 7w1m 318-616 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:467:620_2i13_A_1 2i13 467-620 View model · PDB
Predicted = Low TFS_sp_P17025_ZN182_HUMAN:511:620_5ei9_E_1 5ei9 511-620 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 232:621 467 620 P:A · DNA:C,D 62.3% / 72.7% 100 View · PDB TFS_sp_P17025_ZN182_HUMAN:467:620_2i13_A_1
1 5wjq 232:621 287 565 P:D · DNA:A,B 52.0% / 68.8% 99 View · PDB TFS_sp_P17025_ZN182_HUMAN:287:565_5wjq_D_1
2 5v3m 232:621 261 537 P:C · DNA:A,B 51.6% / 68.2% 100 View · PDB TFS_sp_P17025_ZN182_HUMAN:261:537_5v3m_C_1
3 5v3j 232:621 261 537 P:E · DNA:A,B 51.6% / 68.2% 100 View · PDB TFS_sp_P17025_ZN182_HUMAN:261:537_5v3j_E_1
1 1llm 232:621 232,232 276,276 P:C,D · DNA:A,B 51.1% / 66.7% 51,52 View · PDB DIMER_sp_P17025_ZN182_HUMAN:232:276_1llm_D_1
5 7w1m 232:621 318 616 P:H · DNA:F,G 38.0% / 54.9% 92 View · PDB TFS_sp_P17025_ZN182_HUMAN:318:616_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
26-67PF01352KRAB boxNo overlap with loaded model regions
234-256PF00096Zinc finger, C2H2 typeoverlaps 232-620
264-284PF00096Zinc finger, C2H2 typeoverlaps 232-620
290-312PF00096Zinc finger, C2H2 typeoverlaps 232-620
318-340PF00096Zinc finger, C2H2 typeoverlaps 232-620
346-368PF00096Zinc finger, C2H2 typeoverlaps 232-620
374-396PF00096Zinc finger, C2H2 typeoverlaps 232-620
402-424PF00096Zinc finger, C2H2 typeoverlaps 232-620
430-452PF00096Zinc finger, C2H2 typeoverlaps 232-620
458-480PF00096Zinc finger, C2H2 typeoverlaps 232-620
486-508PF00096Zinc finger, C2H2 typeoverlaps 232-620
514-536PF00096Zinc finger, C2H2 typeoverlaps 232-620
542-564PF00096Zinc finger, C2H2 typeoverlaps 232-620
570-592PF00096Zinc finger, C2H2 typeoverlaps 232-620
598-620PF00096Zinc finger, C2H2 typeoverlaps 232-620