ModCRE DB

Transcription factor

P18146 - EGR1

Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 543 aa

15 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known15
MotifPredictionSourceDNA bindingSupportLogoActions
MA0162.2 Known JASPAR CCCCCGCCCCCGCC Direct PWM Open · Scan
MA0162.3 Known JASPAR TACGCCCACGCATT Direct PWM Open · Scan
MA0162.4 Known JASPAR CCACGCCCACGCCC Direct PWM Open · Scan
MA0162.5 Known JASPAR ACGCCCACGC Direct PWM Open · Scan
M02883_2.00 Known CisBP TACGCCCACGCATT Direct PWM Open · Scan
M02884_2.00 Known CisBP TACGCCCACGCATT Direct PWM Open · Scan
M04437_2.00 Known CisBP CCCGCCCACGCAC Direct PWM Open · Scan
M04438_2.00 Known CisBP CCCGCCCACGCAC Direct PWM Open · Scan
M07927_2.00 Known CisBP CCCCCCCCCCGCCCCCGCAC Direct PWM Open · Scan
M07928_2.00 Known CisBP CCCCGCCCCCGCACC Direct PWM Open · Scan
M07929_2.00 Known CisBP CCCCCCCCCCCGCCCACGCA Direct PWM Open · Scan
M08882_2.00 Known CisBP CCCCCGCCCACGCCCTC Direct PWM Open · Scan
M09506_2.00 Known CisBP CACCCACGCA Direct PWM Open · Scan
M10188_2.00 Known CisBP ACGCCCACGCAT Direct PWM Open · Scan
EGR1_HUMAN.H11MO.0.A Known HOCOMOCO GAGGGCGTGGGCGGGGG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 543 aa
335-420

Region 335-420 0 PWM

Residues
86 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
4R2A
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 335-4201 model
Actions
Predicted = Low TFS_P18146:335:420_4r2a_A_1 4r2a 335-420 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
135-237PF11928Early growth response N-terminal domainNo overlap with loaded model regions
338-362PF00096Zinc finger, C2H2 typeoverlaps 335-420
368-390PF00096Zinc finger, C2H2 typeoverlaps 335-420
396-418PF00096Zinc finger, C2H2 typeoverlaps 335-420
452-530PF11914Domain of unknown function (DUF3432)No overlap with loaded model regions