ModCRE DB

Transcription factor

P19484 - TFEB

Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 476 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
MA0692.1 Known JASPAR ATCACGTGAC Direct PWM Open · Scan
MA0692.2 Known JASPAR CACGTGAC Direct PWM Open · Scan
M02727_2.00 Known CisBP GTCACGTGAC Direct PWM Open · Scan
M02781_2.00 Known CisBP ATCACGTGAC Direct PWM Open · Scan
M04088_2.00 Known CisBP CGCACGTGACC Direct PWM Open · Scan
M04089_2.00 Known CisBP AACATGTGACC Direct PWM Open · Scan
M08718_2.00 Known CisBP CACGTGACC Direct PWM Open · Scan
TFEB_HUMAN.H11MO.0.C Known HOCOMOCO GGTCACGTG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 476 aa
232-294

Region 232-294 0 PWM

Residues
63 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
5I50
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 232-2941 model
Actions
Predicted = Low DIMER_P19484:232:294_5i50_B_1 5i50 232-294 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
4-162PF15951MITF/TFEB/TFEC/TFE3 N-terminusNo overlap with loaded model regions
236-289PF00010Helix-loop-helix DNA-binding domainoverlaps 232-294
321-473PF11851Domain of unknown function (DUF3371)No overlap with loaded model regions