ModCRE DB

Transcription factor

P19532 - TFE3

Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 575 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
MA0831.1 Known JASPAR ATCACGTGAC Direct PWM Open · Scan
MA0831.2 Known JASPAR CACGTGAC Direct PWM Open · Scan
MA0831.3 Known JASPAR GTCACGTGAC Direct PWM Open · Scan
M02773_2.00 Known CisBP ATCACGTGAC Direct PWM Open · Scan
M04058_2.00 Known CisBP CGCACGTGACG Direct PWM Open · Scan
M04059_2.00 Known CisBP CGTCACATGCT Direct PWM Open · Scan
M08709_2.00 Known CisBP TCACGTGACC Direct PWM Open · Scan
TFE3_HUMAN.H11MO.0.B Known HOCOMOCO GGTCACGTGA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 575 aa
343-398

Region 343-398 0 PWM

Residues
56 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
4H10
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 343-3981 model
Actions
Predicted = Low DIMER_P19532:343:398_4h10_B_1 4h10 343-398 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
113-266PF15951MITF/TFEB/TFEC/TFE3 N-terminusNo overlap with loaded model regions
347-400PF00010Helix-loop-helix DNA-binding domainoverlaps 343-398
432-574PF11851Domain of unknown function (DUF3371)No overlap with loaded model regions