ModCRE DB

Transcription factor

P19622 - EN2

Homeobox protein engrailed-2 (Homeobox protein en-2) (Hu-En-2)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 333 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
MA0642.1 Known JASPAR CCCAATTAGC Direct PWM Open · Scan
MA0642.2 Known JASPAR CCCAATTA Direct PWM Open · Scan
MA0642.3 Known JASPAR CCAATTA Direct PWM Open · Scan
M03189_2.00 Known CisBP GTTAATTGGA Direct PWM Open · Scan
M03190_2.00 Known CisBP GCTAATTGGG Direct PWM Open · Scan
M05237_2.00 Known CisBP CTAATTAG Direct PWM Open · Scan
M05238_2.00 Known CisBP ATTAACGAT Direct PWM Open · Scan
M05239_2.00 Known CisBP CTAATTAG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 333 aa
245-300

Region 245-300 0 PWM

Residues
56 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
2HDD
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 245-3001 model
Actions
Predicted = Low DIMER_P19622:245:300_2hdd_B_1 2hdd 245-300 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
245-301PF00046Homeodomainoverlaps 245-300
302-331PF10525Engrailed homeobox C-terminal signature domainNo overlap with loaded model regions