ModCRE DB

Transcription factor

P40763 - STAT3

Signal transducer and activator of transcription 3 (Acute-phase response factor)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 770 aa

11 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known11
MotifPredictionSourceDNA bindingSupportLogoActions
MA0144.2 Known JASPAR CTTCTGGGAAA Direct PWM Open · Scan
MA0144.3 Known JASPAR TTCTGGGAA Direct PWM Open · Scan
M08015_2.00 Known CisBP CATTTCCCGGAAATCACCTG Direct PWM Open · Scan
M08016_2.00 Known CisBP CATTTCCCGGAAG Direct PWM Open · Scan
M08017_2.00 Known CisBP CATTTCCCGGAAATG Direct PWM Open · Scan
M08018_2.00 Known CisBP CATTTCCCGGAAATG Direct PWM Open · Scan
M08172_2.00 Known CisBP TTTCCCAGAAG Direct PWM Open · Scan
M09415_2.00 Known CisBP CATTTCCCGGAA Direct PWM Open · Scan
M11367_2.00 Known CisBP TGGCATTTCCCGGAAATGATT Direct PWM Open · Scan
M11368_2.00 Known CisBP GGATTCCC Direct PWM Open · Scan
STAT3_HUMAN.H11MO.0.A Known HOCOMOCO CATTTCCCGGAA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 770 aa
269-690

Region 269-690 0 PWM

Residues
422 aa
Domains
PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models
1 active PDB
Templates
4Y5W
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 269-6901 model
Actions
Predicted = Low DIMER_P40763:269:690_4y5w_A_1 4y5w 269-690 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-119PF02865STAT protein, protein interaction domainNo overlap with loaded model regions
145-313PF01017STAT transcription factor, coiled-coil domainoverlaps 269-690
326-464PF02864STAT protein, DNA binding domainoverlaps 269-690
488-565PF21354Signal transducer and activator of transcription, linker domainoverlaps 269-690
584-651PF00017SH2 domainoverlaps 269-690