Transcription factor

P41225 - SOX3

Transcription factor SOX-3

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 446 aa

4 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known4

Motif	Prediction	Source	DNA binding	Support	Actions
M05769_2.00	Known	CisBP	CCATTGTGAG	Direct PWM	Open · Scan
M05770_2.00	Known	CisBP	CCATTGTTCT	Direct PWM	Open · Scan
M09391_2.00	Known	CisBP	GCCTTTGTCCC	Direct PWM	Open · Scan
SOX3_HUMAN.H11MO.0.B	Known	HOCOMOCO	GCCTTTGTCCC	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 446 aa

136-209

Residues: 74 aa
Domains: PF00505 · HMG (high mobility group) box PF12336 · SOX transcription factor
3D models: 1 active PDB
Templates: 2GZK
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 136-2091 model

				Actions
Predicted = Low	TFS_P41225:136:209_2gzk_A_1	2gzk	136-209	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
139-207	PF00505	HMG (high mobility group) box	overlaps 136-209
208-302	PF12336	SOX transcription factor	overlaps 136-209