ModCRE DB

Transcription factor

P43699 - NKX2-1

Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 371 aa

2 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2
MotifPredictionSourceDNA bindingSupportLogoActions
M09146_2.00 Known CisBP CTTGAGTGGC Direct PWM Open · Scan
NKX21_HUMAN.H11MO.0.A Known HOCOMOCO CTTGAGTGGC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 371 aa
161-217

Region 161-217 0 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
3RKQ
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 161-2171 model
Actions
Predicted = Low DIMER_P43699:161:217_3rkq_A_1 3rkq 161-217 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
162-218PF00046Homeodomainoverlaps 161-217