ModCRE DB

Transcription factor

P48431 - SOX2

Transcription factor SOX-2

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 317 aa

12 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known12
MotifPredictionSourceDNA bindingSupportLogoActions
MA0143.4 Known JASPAR AAACAATGGAA Direct PWM Open · Scan
MA0143.5 Known JASPAR ACAATGG Direct PWM Open · Scan
MA1962.1 Known JASPAR AATTTGCATAACAATGG Direct PWM Open · Scan
M03519_2.00 Known CisBP GAACAATGGTATTGTTC Direct PWM Open · Scan
M03520_2.00 Known CisBP ATGAATGTTATTCAT Direct PWM Open · Scan
M03521_2.00 Known CisBP GATCAATGTTATTGATG Direct PWM Open · Scan
M03522_2.00 Known CisBP GAACAATAACATTGTTC Direct PWM Open · Scan
M03523_2.00 Known CisBP TATCAATAACATTGATA Direct PWM Open · Scan
M03524_2.00 Known CisBP ATGAATAACATTCAT Direct PWM Open · Scan
M05897_2.00 Known CisBP AACAATAGAA Direct PWM Open · Scan
M09397_2.00 Known CisBP TCCCTTTGTTCTC Direct PWM Open · Scan
SOX2_HUMAN.H11MO.0.A Known HOCOMOCO TCCCTTTGTTCTC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 317 aa
39-111

Region 39-111 0 PWM

Residues
73 aa
Domains
PF00505 · HMG (high mobility group) box PF12336 · SOX transcription factor
3D models
1 active PDB
Templates
1HRY
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 39-1111 model
Actions
Predicted = Low TFS_P48431:39:111_1hry_A_1 1hry 39-111 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
41-109PF00505HMG (high mobility group) boxoverlaps 39-111
110-200PF12336SOX transcription factoroverlaps 39-111