ModCRE DB

Transcription factor

P51508 - ZNF81

Zinc finger protein 81 (HFZ20)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 661 aa

69 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07728_2.00 Known CisBP TCTCAACTGGTGCCACCA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)63
MotifPredictionSourceDNA bindingSupportLogoActions
M00953_2.00 NN 70-40% CisBP ATCTATAT 62.5% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 61.9% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 60.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 60.0% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 60.0% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 59.8% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 59.3% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 59.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 59.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 58.8% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 58.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 57.9% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 56.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 56.8% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 56.6% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 56.5% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 56.1% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 55.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 55.6% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 55.4% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 55.3% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 55.2% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 55.2% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 54.9% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 54.8% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.0% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.9% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 53.9% identity Open · Scan
M07620_2.00 NN 70-40% CisBP TTGGATCTGTGGATTCATGTCTTTCAT 53.5% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 53.2% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 53.1% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 53.0% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 52.8% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 52.7% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 52.5% identity Open · Scan
M08274_2.00 NN 70-40% CisBP TTACTTGCAGCCCAACGCATTCCTAAC 52.4% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 52.4% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 52.2% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 52.2% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 52.1% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 52.1% identity Open · Scan
M07666_2.00 NN 70-40% CisBP ATCTAGCCCCTGCCTACC 51.9% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 51.8% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.7% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 51.7% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 51.7% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 51.5% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 51.4% identity Open · Scan
M07582_2.00 NN 70-40% CisBP TCCCTG 51.3% identity Open · Scan
M07586_2.00 NN 70-40% CisBP GGGACCCGGGTGGGGGCGTCCCCC 51.2% identity Open · Scan
M07618_2.00 NN 70-40% CisBP CCTTTGGTGCTC 51.1% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 51.0% identity Open · Scan
M07767_2.00 NN 70-40% CisBP AAAAACCCCAGA 51.0% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 51.0% identity Open · Scan
M07565_2.00 NN 70-40% CisBP CCTCTGGGGGCTCGTCCA 50.8% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 50.4% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.4% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 50.2% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 50.2% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.0% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 50.0% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_P51508_ZNF81_HUMAN:327:605_5wjq_D_1 ModCRE Homology model GGGGGGGCCAGGGGTTGGCTCTGCCAGG Region 327-605 · 1 3D model Open · Scan
TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3j_E_1 ModCRE Homology model CCCAAGAGGGATAGGGAATGTCTTGG Region 387-661 · 1 3D model Open · Scan
TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3m_C_1 ModCRE Homology model GCCAAGCGGGGGGGAAAAGCTTCGGG Region 387-661 · 1 3D model Open · Scan
TFS_sp_P51508_ZNF81_HUMAN:451:604_2i13_A_1 ModCRE Homology model AGGAGGCGGCCGCATCTGAGT Region 451-604 · 1 3D model Open · Scan
TFS_sp_P51508_ZNF81_HUMAN:467:577_5ei9_E_1 ModCRE Homology model GCCCCCGAGAGGGGTCCG Region 467-577 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 661 aa
327-661

Region 327-661 5 PWM

Residues
335 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 327-6617 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P51508_ZNF81_HUMAN:580:631_1llm_C_1 1llm 580-631 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:327:605_5wjq_D_1 5wjq 327-605 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:332:628_7w1m_H_1 7w1m 332-628 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3j_E_1 5v3j 387-661 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3m_C_1 5v3m 387-661 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:451:604_2i13_A_1 2i13 451-604 View model · PDB
Predicted = Low TFS_sp_P51508_ZNF81_HUMAN:467:577_5ei9_E_1 5ei9 467-577 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 327:661 451 604 P:A · DNA:C,D 57.1% / 70.8% 100 View · PDB TFS_sp_P51508_ZNF81_HUMAN:451:604_2i13_A_1
1 5wjq 327:661 327 605 P:D · DNA:A,B 50.9% / 67.0% 99 View · PDB TFS_sp_P51508_ZNF81_HUMAN:327:605_5wjq_D_1
2 5v3m 327:661 387 661 P:C · DNA:A,B 49.8% / 68.4% 99 View · PDB TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3m_C_1
3 5v3j 327:661 387 661 P:E · DNA:A,B 49.8% / 68.4% 99 View · PDB TFS_sp_P51508_ZNF81_HUMAN:387:661_5v3j_E_1
1 1llm 327:661 580,580 631,631 P:C,D · DNA:A,B 42.3% / 59.6% 59,61 View · PDB DIMER_sp_P51508_ZNF81_HUMAN:580:631_1llm_C_1
5 7w1m 327:661 332 628 P:H · DNA:F,G 36.3% / 51.3% 92 View · PDB TFS_sp_P51508_ZNF81_HUMAN:332:628_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
20-61PF01352KRAB boxNo overlap with loaded model regions
330-352PF00096Zinc finger, C2H2 typeoverlaps 327-661
358-380PF00096Zinc finger, C2H2 typeoverlaps 327-661
386-408PF00096Zinc finger, C2H2 typeoverlaps 327-661
414-436PF00096Zinc finger, C2H2 typeoverlaps 327-661
442-464PF00096Zinc finger, C2H2 typeoverlaps 327-661
470-492PF00096Zinc finger, C2H2 typeoverlaps 327-661
498-520PF00096Zinc finger, C2H2 typeoverlaps 327-661
526-548PF00096Zinc finger, C2H2 typeoverlaps 327-661
554-576PF00096Zinc finger, C2H2 typeoverlaps 327-661
582-604PF00096Zinc finger, C2H2 typeoverlaps 327-661
610-632PF00096Zinc finger, C2H2 typeoverlaps 327-661
638-660PF00096Zinc finger, C2H2 typeoverlaps 327-661