ModCRE DB

Transcription factor

P51786 - ZNF157

Zinc finger protein 157 (Zinc finger protein HZF22)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 506 aa

72 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2
MotifPredictionSourceDNA bindingSupportLogoActions
MA2331.1 Known JASPAR AGGCCAGCAATATACCTTTAC Direct PWM Open · Scan
M07596_2.00 Known CisBP TGTACTGCTGTCCCTCCCAGGACA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)65
MotifPredictionSourceDNA bindingSupportLogoActions
M00953_2.00 NN 70-40% CisBP ATCTATAT 64.7% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 63.5% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 63.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 63.5% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 62.3% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 62.3% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 62.3% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 61.1% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 61.1% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 60.9% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 60.3% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.0% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 59.8% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 59.5% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 58.5% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 58.2% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 57.3% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 57.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 56.9% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 56.9% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 56.8% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 56.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 56.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 56.4% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 56.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 56.2% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 55.9% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 55.9% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 55.4% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 55.3% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 55.0% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 54.3% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 54.2% identity Open · Scan
M07706_2.00 NN 70-40% CisBP GTCTTTGAGAGGGCCCAGATGTTGGACTTA 53.9% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 53.7% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 53.7% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 53.5% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 53.5% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 53.4% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 53.4% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 53.3% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 53.3% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 53.3% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 53.3% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 53.1% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.9% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 52.8% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 52.7% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 52.5% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 52.4% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 52.4% identity Open · Scan
M08390_2.00 NN 70-40% CisBP GCTTTGTTGACTCAC 52.2% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 52.1% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 52.1% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 51.9% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 51.7% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 51.4% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 51.4% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.9% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 50.7% identity Open · Scan
MA0516.1 NN 70-40% JASPAR GCCCCGCCCCCTCCC 50.6% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 50.4% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M07657_2.00 NN 70-40% CisBP CCCCTGCATGTCCCCATTTTT 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_P51786_ZN157_HUMAN:163:437_5v3j_E_1 ModCRE Homology model GGGAAACCCCCAGAGGGGGGGTGAGG Region 163-437 · 1 3D model Open · Scan
TFS_sp_P51786_ZN157_HUMAN:163:437_5v3m_C_1 ModCRE Homology model TGGGGGGGCGGAAAGAGGCCGTGGTC Region 163-437 · 1 3D model Open · Scan
TFS_sp_P51786_ZN157_HUMAN:215:492_5wjq_D_1 ModCRE Homology model GGGGGGGCGGGGCGGCGGGGGCGGGGGG Region 215-492 · 1 3D model Open · Scan
TFS_sp_P51786_ZN157_HUMAN:227:380_2i13_A_1 ModCRE Homology model ATTTTAGTACTCCTAAGCCCG Region 227-380 · 1 3D model Open · Scan
TFS_sp_P51786_ZN157_HUMAN:243:353_5ei9_E_1 ModCRE Homology model GGGGGGGGGGGCGGCCC Region 243-353 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 506 aa
163-492

Region 163-492 5 PWM

Residues
330 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 163-4927 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P51786_ZN157_HUMAN:188:236_1llm_D_1 1llm 188-236 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:163:437_5v3j_E_1 5v3j 163-437 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:163:437_5v3m_C_1 5v3m 163-437 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:190:488_7w1m_H_1 7w1m 190-488 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:215:492_5wjq_D_1 5wjq 215-492 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:227:380_2i13_A_1 2i13 227-380 View model · PDB
Predicted = Low TFS_sp_P51786_ZN157_HUMAN:243:353_5ei9_E_1 5ei9 243-353 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 155:492 227 380 P:A · DNA:C,D 61.0% / 70.8% 100 View · PDB TFS_sp_P51786_ZN157_HUMAN:227:380_2i13_A_1
1 5wjq 155:492 215 492 P:D · DNA:A,B 52.2% / 66.2% 98 View · PDB TFS_sp_P51786_ZN157_HUMAN:215:492_5wjq_D_1
2 5v3m 155:492 163 437 P:C · DNA:A,B 49.8% / 65.8% 99 View · PDB TFS_sp_P51786_ZN157_HUMAN:163:437_5v3m_C_1
3 5v3j 155:492 163 437 P:E · DNA:A,B 49.8% / 65.8% 99 View · PDB TFS_sp_P51786_ZN157_HUMAN:163:437_5v3j_E_1
1 1llm 155:492 188,188 236,236 P:C,D · DNA:A,B 40.8% / 61.2% 56,57 View · PDB DIMER_sp_P51786_ZN157_HUMAN:188:236_1llm_D_1
5 7w1m 155:492 190 488 P:H · DNA:F,G 36.7% / 50.6% 92 View · PDB TFS_sp_P51786_ZN157_HUMAN:190:488_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
26-67PF01352KRAB boxNo overlap with loaded model regions
162-184PF00096Zinc finger, C2H2 typeoverlaps 163-492
190-212PF00096Zinc finger, C2H2 typeoverlaps 163-492
218-240PF00096Zinc finger, C2H2 typeoverlaps 163-492
246-268PF00096Zinc finger, C2H2 typeoverlaps 163-492
274-296PF00096Zinc finger, C2H2 typeoverlaps 163-492
302-324PF00096Zinc finger, C2H2 typeoverlaps 163-492
330-352PF00096Zinc finger, C2H2 typeoverlaps 163-492
358-380PF00096Zinc finger, C2H2 typeoverlaps 163-492
386-408PF00096Zinc finger, C2H2 typeoverlaps 163-492
414-436PF00096Zinc finger, C2H2 typeoverlaps 163-492
442-464PF00096Zinc finger, C2H2 typeoverlaps 163-492
470-492PF00096Zinc finger, C2H2 typeoverlaps 163-492