ModCRE DB

Transcription factor

P52630 - STAT2

Signal transducer and activator of transcription 2 (p113)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 851 aa

5 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known5
MotifPredictionSourceDNA bindingSupportLogoActions
MA0517.1 Known JASPAR TCAGTTTCATTTTCC Direct PWM Open · Scan
MA0517.2 Known JASPAR AGTTTCATTTTCC Direct PWM Open · Scan
M08019_2.00 Known CisBP TTCAGTTTCATTTTC Direct PWM Open · Scan
M09416_2.00 Known CisBP CTTTCAGTTTCATTTTCCT Direct PWM Open · Scan
STAT2_HUMAN.H11MO.0.A Known HOCOMOCO AGGAAAATGAAACTGAAAG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 851 aa
419-691

Region 419-691 0 PWM

Residues
273 aa
Domains
PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models
1 active PDB
Templates
4Y5W
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 419-6911 model
Actions
Predicted = Low DIMER_P52630:419:691_4y5w_A_1 4y5w 419-691 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-122PF02865STAT protein, protein interaction domainNo overlap with loaded model regions
146-308PF01017STAT transcription factor, coiled-coil domainNo overlap with loaded model regions
321-456PF02864STAT protein, DNA binding domainoverlaps 419-691
482-557PF21354Signal transducer and activator of transcription, linker domainoverlaps 419-691
578-648PF00017SH2 domainoverlaps 419-691
783-838PF12188Signal transducer and activator of transcription 2 C terminalNo overlap with loaded model regions