ModCRE DB

Transcription factor

P52736 - ZNF133

Zinc finger protein 133 (Zinc finger protein 150)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 654 aa

49 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07580_2.00 Known CisBP AGGCGCCAATTATACATATGTTGGACCTTC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)43
MotifPredictionSourceDNA bindingSupportLogoActions
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 62.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 60.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 60.0% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 57.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 57.6% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 56.4% identity Open · Scan
M07662_2.00 NN 70-40% CisBP CCTGTGTCCTCCCTGGTCCCC 56.2% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 55.7% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 55.2% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 55.2% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 54.7% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 54.6% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 54.1% identity Open · Scan
M04515_2.00 NN 70-40% CisBP TATGCTATAACAAGCAGCCCC 53.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.3% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 53.3% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 53.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 52.8% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 52.7% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.7% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 52.4% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 52.1% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 52.1% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 52.1% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 51.8% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 51.8% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 51.4% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 51.2% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 51.0% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 50.9% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 50.6% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 50.6% identity Open · Scan
M07645_2.00 NN 70-40% CisBP CTCCTT 50.5% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 50.5% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 50.3% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 50.3% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 50.3% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 50.3% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_P52736_ZN133_HUMAN:297:573_5v3j_E_1 ModCRE Homology model GGGCCGGGGGGGACGAGGGGGTGAGT Region 297-573 · 1 3D model Open · Scan
TFS_sp_P52736_ZN133_HUMAN:297:573_5v3m_C_1 ModCRE Homology model CCGCCCCGGGGGGGGGGGGGGGAGAG Region 297-573 · 1 3D model Open · Scan
TFS_sp_P52736_ZN133_HUMAN:323:601_5wjq_D_1 ModCRE Homology model GGGGAGCGCGGGGGGCGGGGCGGGGGGG Region 323-601 · 1 3D model Open · Scan
TFS_sp_P52736_ZN133_HUMAN:363:516_2i13_A_1 ModCRE Homology model ACTGACTATTACTATGCTATT Region 363-516 · 1 3D model Open · Scan
TFS_sp_P52736_ZN133_HUMAN:435:545_5ei9_E_1 ModCRE Homology model CCCCGGGGGGGGGCGGG Region 435-545 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 654 aa
297-601

Region 297-601 5 PWM

Residues
305 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 297-6016 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P52736_ZN133_HUMAN:408:459_1llm_D_1 1llm 408-459 View model · PDB
Predicted = Low TFS_sp_P52736_ZN133_HUMAN:297:573_5v3j_E_1 5v3j 297-573 View model · PDB
Predicted = Low TFS_sp_P52736_ZN133_HUMAN:297:573_5v3m_C_1 5v3m 297-573 View model · PDB
Predicted = Low TFS_sp_P52736_ZN133_HUMAN:323:601_5wjq_D_1 5wjq 323-601 View model · PDB
Predicted = Low TFS_sp_P52736_ZN133_HUMAN:363:516_2i13_A_1 2i13 363-516 View model · PDB
Predicted = Low TFS_sp_P52736_ZN133_HUMAN:435:545_5ei9_E_1 5ei9 435-545 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 222:626 435 545 P:E · DNA:A,B 71.2% / 86.5% 100 View · PDB TFS_sp_P52736_ZN133_HUMAN:435:545_5ei9_E_1
4 2i13 222:626 363 516 P:A · DNA:C,D 55.8% / 67.5% 100 View · PDB TFS_sp_P52736_ZN133_HUMAN:363:516_2i13_A_1
1 5wjq 222:626 323 601 P:D · DNA:A,B 48.0% / 64.9% 99 View · PDB TFS_sp_P52736_ZN133_HUMAN:323:601_5wjq_D_1
2 5v3m 222:626 297 573 P:C · DNA:A,B 47.7% / 63.9% 100 View · PDB TFS_sp_P52736_ZN133_HUMAN:297:573_5v3m_C_1
3 5v3j 222:626 297 573 P:E · DNA:A,B 47.7% / 63.9% 100 View · PDB TFS_sp_P52736_ZN133_HUMAN:297:573_5v3j_E_1
1 1llm 222:626 408,408 459,459 P:C,D · DNA:A,B 46.2% / 67.3% 59,61 View · PDB DIMER_sp_P52736_ZN133_HUMAN:408:459_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-41PF01352KRAB boxNo overlap with loaded model regions
216-236PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
242-264PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
271-292PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
298-320PF00096Zinc finger, C2H2 typeoverlaps 297-601
326-348PF00096Zinc finger, C2H2 typeoverlaps 297-601
355-376PF00096Zinc finger, C2H2 typeoverlaps 297-601
382-404PF00096Zinc finger, C2H2 typeoverlaps 297-601
410-432PF00096Zinc finger, C2H2 typeoverlaps 297-601
438-460PF00096Zinc finger, C2H2 typeoverlaps 297-601
467-488PF00096Zinc finger, C2H2 typeoverlaps 297-601
495-516PF00096Zinc finger, C2H2 typeoverlaps 297-601
522-544PF00096Zinc finger, C2H2 typeoverlaps 297-601
550-572PF00096Zinc finger, C2H2 typeoverlaps 297-601
606-627PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions