ModCRE DB

Transcription factor

P52952 - NKX2-5

Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 324 aa

16 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known16
MotifPredictionSourceDNA bindingSupportLogoActions
MA0063.2 Known JASPAR ACCACTCAAAA Direct PWM Open · Scan
MA0063.3 Known JASPAR CACTCAA Direct PWM Open · Scan
M00320_2.00 Known CisBP TTTAAGTGG Direct PWM Open · Scan
M00321_2.00 Known CisBP TTAAGTGCTT Direct PWM Open · Scan
M00322_2.00 Known CisBP TTTGTAA Direct PWM Open · Scan
M00323_2.00 Known CisBP TTTAAGTGGTT Direct PWM Open · Scan
M00324_2.00 Known CisBP TTGTTTA Direct PWM Open · Scan
M01507_2.00 Known CisBP TTAAGTG Direct PWM Open · Scan
M01508_2.00 Known CisBP TTAAGTG Direct PWM Open · Scan
M05346_2.00 Known CisBP CTCAAGTGGT Direct PWM Open · Scan
M05347_2.00 Known CisBP GTCAAGTGGT Direct PWM Open · Scan
M05348_2.00 Known CisBP CTCAACGAG Direct PWM Open · Scan
M09163_2.00 Known CisBP TGGAGAGG Direct PWM Open · Scan
M10742_2.00 Known CisBP TCAAGTG Direct PWM Open · Scan
M10743_2.00 Known CisBP CTTAATTG Direct PWM Open · Scan
NKX25_HUMAN.H11MO.0.B Known HOCOMOCO TGGAGAGG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 324 aa
138-194

Region 138-194 0 PWM

Residues
57 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
3RKQ
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 138-1941 model
Actions
Predicted = Low DIMER_P52952:138:194_3rkq_A_1 3rkq 138-194 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
139-195PF00046Homeodomainoverlaps 138-194